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Amphiregulin promotes cardiac fibrosis post myocardial infarction by inducing the endothelial-mesenchymal transition via the EGFR pathway in endothelial cells.
Liu L, Song S, Zhang YP, Wang D, Zhou Z, Chen Y, Jin X, Hu CF, Shen CX. Liu L, et al. Among authors: jin x. Exp Cell Res. 2020 May 15;390(2):111950. doi: 10.1016/j.yexcr.2020.111950. Epub 2020 Mar 15. Exp Cell Res. 2020. Retraction in: Exp Cell Res. 2024 Sep 1;442(1):114207. doi: 10.1016/j.yexcr.2024.114207. PMID: 32188578 Retracted.
Amphiregulin enhances cardiac fibrosis and aggravates cardiac dysfunction in mice with experimental myocardial infarction partly through activating EGFR-dependent pathway.
Liu L, Jin X, Hu CF, Zhang YP, Zhou Z, Li R, Shen CX. Liu L, et al. Among authors: jin x. Basic Res Cardiol. 2018 Jan 18;113(2):12. doi: 10.1007/s00395-018-0669-y. Basic Res Cardiol. 2018. Retraction in: Basic Res Cardiol. 2022 Nov 7;117(1):54. doi: 10.1007/s00395-022-00963-2. PMID: 29349588 Retracted.
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