Vendrell I - Search Results

1

TEX264 coordinates p97- and SPRTN-mediated resolution of topoisomerase 1-DNA adducts.

Fielden J, Wiseman K, Torrecilla I, Li S, Hume S, Chiang SC, Ruggiano A, Narayan Singh A, Freire R, Hassanieh S, Domingo E, Vendrell I, Fischer R, Kessler BM, Maughan TS, El-Khamisy SF, Ramadan K. Fielden J, et al. Among authors: vendrell i. Nat Commun. 2020 Mar 9;11(1):1274. doi: 10.1038/s41467-020-15000-w. Nat Commun. 2020. PMID: 32152270 Free PMC article.

2

Metalloprotease SPRTN/DVC1 Orchestrates Replication-Coupled DNA-Protein Crosslink Repair.

Vaz B, Popovic M, Newman JA, Fielden J, Aitkenhead H, Halder S, Singh AN, Vendrell I, Fischer R, Torrecilla I, Drobnitzky N, Freire R, Amor DJ, Lockhart PJ, Kessler BM, McKenna GW, Gileadi O, Ramadan K. Vaz B, et al. Among authors: vendrell i. Mol Cell. 2016 Nov 17;64(4):704-719. doi: 10.1016/j.molcel.2016.09.032. Epub 2016 Oct 27. Mol Cell. 2016. PMID: 27871366 Free PMC article.

3

Modulation of proteostasis counteracts oxidative stress and affects DNA base excision repair capacity in ATM-deficient cells.

Poletto M, Yang D, Fletcher SC, Vendrell I, Fischer R, Legrand AJ, Dianov GL. Poletto M, et al. Among authors: vendrell i. Nucleic Acids Res. 2017 Sep 29;45(17):10042-10055. doi: 10.1093/nar/gkx635. Nucleic Acids Res. 2017. PMID: 28973444 Free PMC article.

4

SPRTN protease and checkpoint kinase 1 cross-activation loop safeguards DNA replication.

Halder S, Torrecilla I, Burkhalter MD, Popović M, Fielden J, Vaz B, Oehler J, Pilger D, Lessel D, Wiseman K, Singh AN, Vendrell I, Fischer R, Philipp M, Ramadan K. Halder S, et al. Among authors: vendrell i. Nat Commun. 2019 Jul 17;10(1):3142. doi: 10.1038/s41467-019-11095-y. Nat Commun. 2019. PMID: 31316063 Free PMC article.

5

RASSF1A is required for the maintenance of nuclear actin levels.

Chatzifrangkeskou M, Pefani DE, Eyres M, Vendrell I, Fischer R, Pankova D, O'Neill E. Chatzifrangkeskou M, et al. Among authors: vendrell i. EMBO J. 2019 Aug 15;38(16):e101168. doi: 10.15252/embj.2018101168. Epub 2019 Jun 7. EMBO J. 2019. PMID: 31414556 Free PMC article.

6

E2F1 proteolysis via SCF-cyclin F underlies synthetic lethality between cyclin F loss and Chk1 inhibition.

Burdova K, Yang H, Faedda R, Hume S, Chauhan J, Ebner D, Kessler BM, Vendrell I, Drewry DH, Wells CI, Hatch SB, Dianov GL, Buffa FM, D'Angiolella V. Burdova K, et al. Among authors: vendrell i. EMBO J. 2019 Oct 15;38(20):e101443. doi: 10.15252/embj.2018101443. Epub 2019 Aug 19. EMBO J. 2019. PMID: 31424118 Free PMC article.

7

The Bloom syndrome complex senses RPA-coated single-stranded DNA to restart stalled replication forks.

Shorrocks AK, Jones SE, Tsukada K, Morrow CA, Belblidia Z, Shen J, Vendrell I, Fischer R, Kessler BM, Blackford AN. Shorrocks AK, et al. Among authors: vendrell i. Nat Commun. 2021 Jan 26;12(1):585. doi: 10.1038/s41467-020-20818-5. Nat Commun. 2021. PMID: 33500419 Free PMC article.

8

SPRTN protease-cleaved MRE11 decreases DNA repair and radiosensitises cancer cells.

Na J, Newman JA, Then CK, Syed J, Vendrell I, Torrecilla I, Ellermann S, Ramadan K, Fischer R, Kiltie AE. Na J, et al. Among authors: vendrell i. Cell Death Dis. 2021 Feb 8;12(2):165. doi: 10.1038/s41419-021-03437-w. Cell Death Dis. 2021. PMID: 33558481 Free PMC article.

9

p97/VCP inhibition causes excessive MRE11-dependent DNA end resection promoting cell killing after ionizing radiation.

Kilgas S, Singh AN, Paillas S, Then CK, Torrecilla I, Nicholson J, Browning L, Vendrell I, Konietzny R, Kessler BM, Kiltie AE, Ramadan K. Kilgas S, et al. Among authors: vendrell i. Cell Rep. 2021 May 25;35(8):109153. doi: 10.1016/j.celrep.2021.109153. Cell Rep. 2021. PMID: 34038735 Free PMC article.

10

Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation.

Chen Z, Ioris RM, Richardson S, Van Ess AN, Vendrell I, Kessler BM, Buffa FM, Busino L, Clifford SC, Bullock AN, D'Angiolella V. Chen Z, et al. Among authors: vendrell i. Cell Death Differ. 2022 Oct;29(10):1955-1969. doi: 10.1038/s41418-022-00983-4. Epub 2022 Apr 4. Cell Death Differ. 2022. PMID: 35379950 Free PMC article.

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