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Direct Extracellular NAMPT Involvement in Pulmonary Hypertension and Vascular Remodeling. Transcriptional Regulation by SOX and HIF-2α.
Sun X, Sun BL, Babicheva A, Vanderpool R, Oita RC, Casanova N, Tang H, Gupta A, Lynn H, Gupta G, Rischard F, Sammani S, Kempf CL, Moreno-Vinasco L, Ahmed M, Camp SM, Wang J, Desai AA, Yuan JX, Garcia JGN. Sun X, et al. Among authors: wang j. Am J Respir Cell Mol Biol. 2020 Jul;63(1):92-103. doi: 10.1165/rcmb.2019-0164OC. Am J Respir Cell Mol Biol. 2020. PMID: 32142369 Free PMC article.
Divergent changes of p53 in pulmonary arterial endothelial and smooth muscle cells involved in the development of pulmonary hypertension.
Wang Z, Yang K, Zheng Q, Zhang C, Tang H, Babicheva A, Jiang Q, Li M, Chen Y, Carr SG, Wu K, Zhang Q, Balistrieri A, Wang C, Song S, Ayon RJ, Desai AA, Black SM, Garcia JGN, Makino A, Yuan JX, Lu W, Wang J. Wang Z, et al. Among authors: wang j, wang c. Am J Physiol Lung Cell Mol Physiol. 2019 Jan 1;316(1):L216-L228. doi: 10.1152/ajplung.00538.2017. Epub 2018 Oct 25. Am J Physiol Lung Cell Mol Physiol. 2019. PMID: 30358436 Free PMC article.
Pathogenic Role of mTORC1 and mTORC2 in Pulmonary Hypertension.
Tang H, Wu K, Wang J, Vinjamuri S, Gu Y, Song S, Wang Z, Zhang Q, Balistrieri A, Ayon RJ, Rischard F, Vanderpool R, Chen J, Zhou G, Desai AA, Black SM, Garcia JGN, Yuan JX, Makino A. Tang H, et al. Among authors: wang j, wang z. JACC Basic Transl Sci. 2018 Dec 31;3(6):744-762. doi: 10.1016/j.jacbts.2018.08.009. eCollection 2018 Dec. JACC Basic Transl Sci. 2018. PMID: 30623134 Free PMC article.
Endothelial platelet-derived growth factor-mediated activation of smooth muscle platelet-derived growth factor receptors in pulmonary arterial hypertension.
Wu K, Tang H, Lin R, Carr SG, Wang Z, Babicheva A, Ayon RJ, Jain PP, Xiong M, Rodriguez M, Rahimi S, Balistrieri F, Rahimi S, Valdez-Jasso D, Simonson TS, Desai AA, Garcia JGN, Shyy JY, Thistlethwaite PA, Wang J, Makino A, Yuan JX. Wu K, et al. Among authors: wang z, wang j. Pulm Circ. 2020 Sep 10;10(3):2045894020948470. doi: 10.1177/2045894020948470. eCollection 2020 Jul-Sep. Pulm Circ. 2020. PMID: 33294172 Free PMC article.
Transcriptomic profiles in pulmonary arterial hypertension associate with disease severity and identify novel candidate genes.
Romanoski CE, Qi X, Sangam S, Vanderpool RR, Stearman RS, Conklin A, Gonzalez-Garay M, Rischard F, Ayon RJ, Wang J, Simonson T, Babicheva A, Shi Y, Tang H, Makino A, Kanthi Y, Geraci MW, Garcia JGN, Yuan JX, Desai AA. Romanoski CE, et al. Among authors: wang j. Pulm Circ. 2020 Dec 7;10(4):2045894020968531. doi: 10.1177/2045894020968531. eCollection 2020 Oct-Dec. Pulm Circ. 2020. PMID: 33343881 Free PMC article.
Endothelial upregulation of mechanosensitive channel Piezo1 in pulmonary hypertension.
Wang Z, Chen J, Babicheva A, Jain PP, Rodriguez M, Ayon RJ, Ravellette KS, Wu L, Balistrieri F, Tang H, Wu X, Zhao T, Black SM, Desai AA, Garcia JGN, Sun X, Shyy JY, Valdez-Jasso D, Thistlethwaite PA, Makino A, Wang J, Yuan JX. Wang Z, et al. Among authors: wang j. Am J Physiol Cell Physiol. 2021 Dec 1;321(6):C1010-C1027. doi: 10.1152/ajpcell.00147.2021. Epub 2021 Oct 20. Am J Physiol Cell Physiol. 2021. PMID: 34669509 Free PMC article.
TRPC6, a therapeutic target for pulmonary hypertension.
Jain PP, Lai N, Xiong M, Chen J, Babicheva A, Zhao T, Parmisano S, Zhao M, Paquin C, Matti M, Powers R, Balistrieri A, Kim NH, Valdez-Jasso D, Thistlethwaite PA, Shyy JY, Wang J, Garcia JGN, Makino A, Yuan JX. Jain PP, et al. Among authors: wang j. Am J Physiol Lung Cell Mol Physiol. 2021 Dec 1;321(6):L1161-L1182. doi: 10.1152/ajplung.00159.2021. Epub 2021 Oct 27. Am J Physiol Lung Cell Mol Physiol. 2021. PMID: 34704831 Free PMC article.
Endothelial eNAMPT drives EndMT and preclinical PH: rescue by an eNAMPT-neutralizing mAb.
Ahmed M, Zaghloul N, Zimmerman P, Casanova NG, Sun X, Song JH, Hernon VR, Sammani S, Rischard F, Rafikova O, Rafikov R, Makino A, Kempf CL, Camp SM, Wang J, Desai AA, Lussier Y, Yuan JX, Garcia JGN. Ahmed M, et al. Among authors: wang j. Pulm Circ. 2021 Nov 12;11(4):20458940211059712. doi: 10.1177/20458940211059712. eCollection 2021 Oct-Dec. Pulm Circ. 2021. PMID: 34790349 Free PMC article.
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