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NOX4 Inhibition Potentiates Immunotherapy by Overcoming Cancer-Associated Fibroblast-Mediated CD8 T-cell Exclusion from Tumors.
Ford K, Hanley CJ, Mellone M, Szyndralewiez C, Heitz F, Wiesel P, Wood O, Machado M, Lopez MA, Ganesan AP, Wang C, Chakravarthy A, Fenton TR, King EV, Vijayanand P, Ottensmeier CH, Al-Shamkhani A, Savelyeva N, Thomas GJ. Ford K, et al. Among authors: savelyeva n. Cancer Res. 2020 May 1;80(9):1846-1860. doi: 10.1158/0008-5472.CAN-19-3158. Epub 2020 Mar 2. Cancer Res. 2020. PMID: 32122909 Free PMC article.
DNA vaccines to attack cancer.
Stevenson FK, Ottensmeier CH, Johnson P, Zhu D, Buchan SL, McCann KJ, Roddick JS, King AT, McNicholl F, Savelyeva N, Rice J. Stevenson FK, et al. Among authors: savelyeva n. Proc Natl Acad Sci U S A. 2004 Oct 5;101 Suppl 2(Suppl 2):14646-52. doi: 10.1073/pnas.0404896101. Epub 2004 Aug 3. Proc Natl Acad Sci U S A. 2004. PMID: 15292504 Free PMC article. Review.
Gene expression analysis of TIL rich HPV-driven head and neck tumors reveals a distinct B-cell signature when compared to HPV independent tumors.
Wood O, Woo J, Seumois G, Savelyeva N, McCann KJ, Singh D, Jones T, Peel L, Breen MS, Ward M, Garrido Martin E, Sanchez-Elsner T, Thomas G, Vijayanand P, Woelk CH, King E, Ottensmeier C; SPARC Consortium. Wood O, et al. Among authors: savelyeva n. Oncotarget. 2016 Aug 30;7(35):56781-56797. doi: 10.18632/oncotarget.10788. Oncotarget. 2016. PMID: 27462861 Free PMC article.
A plant-expressed conjugate vaccine breaks CD4(+) tolerance and induces potent immunity against metastatic Her2(+) breast cancer.
Chotprakaikiat W, Allen A, Bui-Minh D, Harden E, Jobsri J, Cavallo F, Gleba Y, Stevenson FK, Ottensmeier C, Klimyuk V, Savelyeva N. Chotprakaikiat W, et al. Among authors: savelyeva n. Oncoimmunology. 2016 Apr 22;5(6):e1166323. doi: 10.1080/2162402X.2016.1166323. eCollection 2016 Jun. Oncoimmunology. 2016. PMID: 27471642 Free PMC article.
Linear doggybone DNA vaccine induces similar immunological responses to conventional plasmid DNA independently of immune recognition by TLR9 in a pre-clinical model.
Allen A, Wang C, Caproni LJ, Sugiyarto G, Harden E, Douglas LR, Duriez PJ, Karbowniczek K, Extance J, Rothwell PJ, Orefo I, Tite JP, Stevenson FK, Ottensmeier CH, Savelyeva N. Allen A, et al. Among authors: savelyeva n. Cancer Immunol Immunother. 2018 Apr;67(4):627-638. doi: 10.1007/s00262-017-2111-y. Epub 2018 Jan 12. Cancer Immunol Immunother. 2018. PMID: 29330557 Free PMC article.
Targeting Head and Neck Cancer by Vaccination.
Wang C, Dickie J, Sutavani RV, Pointer C, Thomas GJ, Savelyeva N. Wang C, et al. Among authors: savelyeva n. Front Immunol. 2018 Apr 23;9:830. doi: 10.3389/fimmu.2018.00830. eCollection 2018. Front Immunol. 2018. PMID: 29740440 Free PMC article. Review.
HNSCC: Tumour Antigens and Their Targeting by Immunotherapy.
von Witzleben A, Wang C, Laban S, Savelyeva N, Ottensmeier CH. von Witzleben A, et al. Among authors: savelyeva n. Cells. 2020 Sep 15;9(9):2103. doi: 10.3390/cells9092103. Cells. 2020. PMID: 32942747 Free PMC article. Review.
Novel players: tissue-resident memory B cells.
Savelyeva N, Ottensmeier CH. Savelyeva N, et al. Blood. 2020 Dec 10;136(24):2722-2723. doi: 10.1182/blood.2020007890. Blood. 2020. PMID: 33301032 Free article. No abstract available.
34 results