Denny JC - Search Results

1

Leveraging Human Genetics to Identify Safety Signals Prior to Drug Marketing Approval and Clinical Use.

Jerome RN, Joly MM, Kennedy N, Shirey-Rice JK, Roden DM, Bernard GR, Holroyd KJ, Denny JC, Pulley JM. Jerome RN, et al. Among authors: denny jc. Drug Saf. 2020 Jun;43(6):567-582. doi: 10.1007/s40264-020-00915-6. Drug Saf. 2020. PMID: 32112228 Free PMC article.

2

PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene-disease associations.

Denny JC, Ritchie MD, Basford MA, Pulley JM, Bastarache L, Brown-Gentry K, Wang D, Masys DR, Roden DM, Crawford DC. Denny JC, et al. Bioinformatics. 2010 May 1;26(9):1205-10. doi: 10.1093/bioinformatics/btq126. Epub 2010 Mar 24. Bioinformatics. 2010. PMID: 20335276 Free PMC article.

3

Robust replication of genotype-phenotype associations across multiple diseases in an electronic medical record.

Ritchie MD, Denny JC, Crawford DC, Ramirez AH, Weiner JB, Pulley JM, Basford MA, Brown-Gentry K, Balser JR, Masys DR, Haines JL, Roden DM. Ritchie MD, et al. Among authors: denny jc. Am J Hum Genet. 2010 Apr 9;86(4):560-72. doi: 10.1016/j.ajhg.2010.03.003. Epub 2010 Apr 1. Am J Hum Genet. 2010. PMID: 20362271 Free PMC article.

4

An analytical approach to characterize morbidity profile dissimilarity between distinct cohorts using electronic medical records.

Schildcrout JS, Basford MA, Pulley JM, Masys DR, Roden DM, Wang D, Chute CG, Kullo IJ, Carrell D, Peissig P, Kho A, Denny JC. Schildcrout JS, et al. Among authors: denny jc. J Biomed Inform. 2010 Dec;43(6):914-23. doi: 10.1016/j.jbi.2010.07.011. Epub 2010 Aug 3. J Biomed Inform. 2010. PMID: 20688191 Free PMC article.

5

Assessing the accuracy of observer-reported ancestry in a biorepository linked to electronic medical records.

Dumitrescu L, Ritchie MD, Brown-Gentry K, Pulley JM, Basford M, Denny JC, Oksenberg JR, Roden DM, Haines JL, Crawford DC. Dumitrescu L, et al. Among authors: denny jc. Genet Med. 2010 Oct;12(10):648-50. doi: 10.1097/GIM.0b013e3181efe2df. Genet Med. 2010. PMID: 20733501 Free PMC article.

6

Identification of genomic predictors of atrioventricular conduction: using electronic medical records as a tool for genome science.

Denny JC, Ritchie MD, Crawford DC, Schildcrout JS, Ramirez AH, Pulley JM, Basford MA, Masys DR, Haines JL, Roden DM. Denny JC, et al. Circulation. 2010 Nov 16;122(20):2016-21. doi: 10.1161/CIRCULATIONAHA.110.948828. Epub 2010 Nov 1. Circulation. 2010. PMID: 21041692 Free PMC article.

7

Modulators of normal electrocardiographic intervals identified in a large electronic medical record.

Ramirez AH, Schildcrout JS, Blakemore DL, Masys DR, Pulley JM, Basford MA, Roden DM, Denny JC. Ramirez AH, et al. Among authors: denny jc. Heart Rhythm. 2011 Feb;8(2):271-7. doi: 10.1016/j.hrthm.2010.10.034. Epub 2010 Oct 29. Heart Rhythm. 2011. PMID: 21044898 Free PMC article.

8

The eMERGE Network: a consortium of biorepositories linked to electronic medical records data for conducting genomic studies.

McCarty CA, Chisholm RL, Chute CG, Kullo IJ, Jarvik GP, Larson EB, Li R, Masys DR, Ritchie MD, Roden DM, Struewing JP, Wolf WA; eMERGE Team. McCarty CA, et al. BMC Med Genomics. 2011 Jan 26;4:13. doi: 10.1186/1755-8794-4-13. BMC Med Genomics. 2011. PMID: 21269473 Free PMC article.

9

Knowledge-driven multi-locus analysis reveals gene-gene interactions influencing HDL cholesterol level in two independent EMR-linked biobanks.

Turner SD, Berg RL, Linneman JG, Peissig PL, Crawford DC, Denny JC, Roden DM, McCarty CA, Ritchie MD, Wilke RA. Turner SD, et al. Among authors: denny jc. PLoS One. 2011 May 11;6(5):e19586. doi: 10.1371/journal.pone.0019586. PLoS One. 2011. PMID: 21589926 Free PMC article.

10

Facilitating pharmacogenetic studies using electronic health records and natural-language processing: a case study of warfarin.

Xu H, Jiang M, Oetjens M, Bowton EA, Ramirez AH, Jeff JM, Basford MA, Pulley JM, Cowan JD, Wang X, Ritchie MD, Masys DR, Roden DM, Crawford DC, Denny JC. Xu H, et al. Among authors: denny jc. J Am Med Inform Assoc. 2011 Jul-Aug;18(4):387-91. doi: 10.1136/amiajnl-2011-000208. J Am Med Inform Assoc. 2011. PMID: 21672908 Free PMC article.

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