Deguchi S - Search Results

1

Comparison of commercially available media for hepatic differentiation and hepatocyte maintenance.

Toba Y, Deguchi S, Mimura N, Sakamoto A, Harada K, Hirata K, Takayama K, Mizuguchi H. Toba Y, et al. Among authors: deguchi s. PLoS One. 2020 Feb 27;15(2):e0229654. doi: 10.1371/journal.pone.0229654. eCollection 2020. PLoS One. 2020. PMID: 32106262 Free PMC article.

2

Modeling of Hepatic Drug Metabolism and Responses in CYP2C19 Poor Metabolizer Using Genetically Manipulated Human iPS cells.

Deguchi S, Yamashita T, Igai K, Harada K, Toba Y, Hirata K, Takayama K, Mizuguchi H. Deguchi S, et al. Drug Metab Dispos. 2019 Jun;47(6):632-638. doi: 10.1124/dmd.119.086322. Epub 2019 Apr 8. Drug Metab Dispos. 2019. PMID: 30962288

3

Establishment of SLC15A1/PEPT1-Knockout Human-Induced Pluripotent Stem Cell Line for Intestinal Drug Absorption Studies.

Kawai K, Negoro R, Ichikawa M, Yamashita T, Deguchi S, Harada K, Hirata K, Takayama K, Mizuguchi H. Kawai K, et al. Among authors: deguchi s. Mol Ther Methods Clin Dev. 2019 Nov 21;17:49-57. doi: 10.1016/j.omtm.2019.11.008. eCollection 2020 Jun 12. Mol Ther Methods Clin Dev. 2019. PMID: 31890740 Free PMC article.

4

Tolloid-Like 1 Negatively Regulates Hepatic Differentiation of Human Induced Pluripotent Stem Cells Through Transforming Growth Factor Beta Signaling.

Kiso A, Toba Y, Tsutsumi S, Deguchi S, Igai K, Koshino S, Tanaka Y, Takayama K, Mizuguchi H. Kiso A, et al. Among authors: deguchi s. Hepatol Commun. 2020 Jan 2;4(2):255-267. doi: 10.1002/hep4.1466. eCollection 2020 Feb. Hepatol Commun. 2020. PMID: 32025609 Free PMC article.

5

Generation of Human Induced Pluripotent Stem Cell-Derived Hepatocyte-Like Cells for Cellular Medicine.

Deguchi S, Takayama K, Mizuguchi H. Deguchi S, et al. Biol Pharm Bull. 2020;43(4):608-615. doi: 10.1248/bpb.b19-00740. Biol Pharm Bull. 2020. PMID: 32238703 Free article. Review.

6

Establishment of MDR1-knockout human induced pluripotent stem cell line.

Negoro R, Kawai K, Ichikawa M, Deguchi S, Takayama K, Mizuguchi H. Negoro R, et al. Among authors: deguchi s. Drug Metab Pharmacokinet. 2020 Jun;35(3):288-296. doi: 10.1016/j.dmpk.2020.01.009. Epub 2020 Feb 10. Drug Metab Pharmacokinet. 2020. PMID: 32303458

7

Modeling SARS-CoV-2 infection and its individual differences with ACE2-expressing human iPS cells.

Sano E, Deguchi S, Sakamoto A, Mimura N, Hirabayashi A, Muramoto Y, Noda T, Yamamoto T, Takayama K. Sano E, et al. Among authors: deguchi s. iScience. 2021 May 21;24(5):102428. doi: 10.1016/j.isci.2021.102428. Epub 2021 Apr 16. iScience. 2021. PMID: 33880436 Free PMC article.

8

Usability of Polydimethylsiloxane-Based Microfluidic Devices in Pharmaceutical Research Using Human Hepatocytes.

Deguchi S, Tsuda M, Kosugi K, Sakamoto A, Mimura N, Negoro R, Sano E, Nobe T, Maeda K, Kusuhara H, Mizuguchi H, Yamashita F, Torisawa YS, Takayama K. Deguchi S, et al. ACS Biomater Sci Eng. 2021 Aug 9;7(8):3648-3657. doi: 10.1021/acsbiomaterials.1c00642. Epub 2021 Jul 20. ACS Biomater Sci Eng. 2021. PMID: 34283567

9

SARS-CoV-2 research using human pluripotent stem cells and organoids.

Deguchi S, Serrano-Aroca Á, Tambuwala MM, Uhal BD, Brufsky AM, Takayama K. Deguchi S, et al. Stem Cells Transl Med. 2021 Nov;10(11):1491-1499. doi: 10.1002/sctm.21-0183. Epub 2021 Jul 24. Stem Cells Transl Med. 2021. PMID: 34302450 Free PMC article. Review.

10

In Vitro Model for a Drug Assessment of Cytochrome P450 Family 3 Subfamily A Member 4 Substrates Using Human Induced Pluripotent Stem Cells and Genome Editing Technology.

Deguchi S, Shintani T, Harada K, Okamoto T, Takemura A, Hirata K, Ito K, Takayama K, Mizuguchi H. Deguchi S, et al. Hepatol Commun. 2021 May 5;5(8):1385-1399. doi: 10.1002/hep4.1729. eCollection 2021 Aug. Hepatol Commun. 2021. PMID: 34430783 Free PMC article.

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