Clevers H - Search Results

1

Mutational signature in colorectal cancer caused by genotoxic pks⁺ E. coli.

Pleguezuelos-Manzano C, Puschhof J, Rosendahl Huber A, van Hoeck A, Wood HM, Nomburg J, Gurjao C, Manders F, Dalmasso G, Stege PB, Paganelli FL, Geurts MH, Beumer J, Mizutani T, Miao Y, van der Linden R, van der Elst S; Genomics England Research Consortium; Garcia KC, Top J, Willems RJL, Giannakis M, Bonnet R, Quirke P, Meyerson M, Cuppen E, van Boxtel R, Clevers H. Pleguezuelos-Manzano C, et al. Among authors: clevers h. Nature. 2020 Apr;580(7802):269-273. doi: 10.1038/s41586-020-2080-8. Epub 2020 Feb 27. Nature. 2020. PMID: 32106218 Free PMC article.

2

APC, signal transduction and genetic instability in colorectal cancer.

Fodde R, Smits R, Clevers H. Fodde R, et al. Among authors: clevers h. Nat Rev Cancer. 2001 Oct;1(1):55-67. doi: 10.1038/35094067. Nat Rev Cancer. 2001. PMID: 11900252 Review.

3

The Wnt/beta-catenin pathway regulates cardiac valve formation.

Hurlstone AF, Haramis AP, Wienholds E, Begthel H, Korving J, Van Eeden F, Cuppen E, Zivkovic D, Plasterk RH, Clevers H. Hurlstone AF, et al. Among authors: clevers h. Nature. 2003 Oct 9;425(6958):633-7. doi: 10.1038/nature02028. Nature. 2003. PMID: 14534590 Free article.

4

EphB receptor activity suppresses colorectal cancer progression.

Batlle E, Bacani J, Begthel H, Jonkheer S, Gregorieff A, van de Born M, Malats N, Sancho E, Boon E, Pawson T, Gallinger S, Pals S, Clevers H. Batlle E, et al. Among authors: clevers h. Nature. 2005 Jun 23;435(7045):1126-30. doi: 10.1038/nature03626. Nature. 2005. PMID: 15973414

5

Efficient double fragmentation ChIP-seq provides nucleotide resolution protein-DNA binding profiles.

Mokry M, Hatzis P, de Bruijn E, Koster J, Versteeg R, Schuijers J, van de Wetering M, Guryev V, Clevers H, Cuppen E. Mokry M, et al. Among authors: clevers h. PLoS One. 2010 Nov 30;5(11):e15092. doi: 10.1371/journal.pone.0015092. PLoS One. 2010. PMID: 21152096 Free PMC article.

6

The cancer stem cell: premises, promises and challenges.

Clevers H. Clevers H. Nat Med. 2011 Mar;17(3):313-9. doi: 10.1038/nm.2304. Nat Med. 2011. PMID: 21386835 Review.

7

Integrated genome-wide analysis of transcription factor occupancy, RNA polymerase II binding and steady-state RNA levels identify differentially regulated functional gene classes.

Mokry M, Hatzis P, Schuijers J, Lansu N, Ruzius FP, Clevers H, Cuppen E. Mokry M, et al. Among authors: clevers h. Nucleic Acids Res. 2012 Jan;40(1):148-58. doi: 10.1093/nar/gkr720. Epub 2011 Sep 13. Nucleic Acids Res. 2012. PMID: 21914722 Free PMC article.

8

Controlled gene expression in primary Lgr5 organoid cultures.

Koo BK, Stange DE, Sato T, Karthaus W, Farin HF, Huch M, van Es JH, Clevers H. Koo BK, et al. Among authors: clevers h. Nat Methods. 2011 Dec 4;9(1):81-3. doi: 10.1038/nmeth.1802. Nat Methods. 2011. PMID: 22138822

9

Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5⁺ stem cell.

Yui S, Nakamura T, Sato T, Nemoto Y, Mizutani T, Zheng X, Ichinose S, Nagaishi T, Okamoto R, Tsuchiya K, Clevers H, Watanabe M. Yui S, et al. Among authors: clevers h. Nat Med. 2012 Mar 11;18(4):618-23. doi: 10.1038/nm.2695. Nat Med. 2012. PMID: 22406745

10

Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors.

Koo BK, Spit M, Jordens I, Low TY, Stange DE, van de Wetering M, van Es JH, Mohammed S, Heck AJ, Maurice MM, Clevers H. Koo BK, et al. Among authors: clevers h. Nature. 2012 Aug 30;488(7413):665-9. doi: 10.1038/nature11308. Nature. 2012. PMID: 22895187

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