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Epigenetic therapy inhibits metastases by disrupting premetastatic niches.
Lu Z, Zou J, Li S, Topper MJ, Tao Y, Zhang H, Jiao X, Xie W, Kong X, Vaz M, Li H, Cai Y, Xia L, Huang P, Rodgers K, Lee B, Riemer JB, Day CP, Yen RC, Cui Y, Wang Y, Wang Y, Zhang W, Easwaran H, Hulbert A, Kim K, Juergens RA, Yang SC, Battafarano RJ, Bush EL, Broderick SR, Cattaneo SM, Brahmer JR, Rudin CM, Wrangle J, Mei Y, Kim YJ, Zhang B, Wang KK, Forde PM, Margolick JB, Nelkin BD, Zahnow CA, Pardoll DM, Housseau F, Baylin SB, Shen L, Brock MV. Lu Z, et al. Among authors: lee b. Nature. 2020 Mar;579(7798):284-290. doi: 10.1038/s41586-020-2054-x. Epub 2020 Feb 26. Nature. 2020. PMID: 32103175 Free PMC article.
A murine xenograft model of spontaneous metastases of human lung adenocarcinoma.
Harris JE Jr, Shin J, Lee B, Pelosky K, Hooker CM, Harbom K, Hulbert A, Zahnow C, Yang SC, Baylin S, Brayton C, Brock MV. Harris JE Jr, et al. Among authors: lee b. J Surg Res. 2011 Nov;171(1):e75-9. doi: 10.1016/j.jss.2011.06.058. Epub 2011 Jul 22. J Surg Res. 2011. PMID: 21872887 Free PMC article.
Human immunodeficiency virus infection as a prognostic factor in surgical patients with non-small cell lung cancer.
Hooker CM, Meguid RA, Hulbert A, Taylor JT, Shin J, Wrangle J, Rodgers K, Lee B, Laskshmanan S, Brown T, Meneshian A, Sussman M, Keruly J, Moore RD, Yang SC, Brock MV. Hooker CM, et al. Among authors: lee b. Ann Thorac Surg. 2012 Feb;93(2):405-12. doi: 10.1016/j.athoracsur.2011.11.012. Ann Thorac Surg. 2012. PMID: 22269705 Free PMC article.
Combination epigenetic therapy has efficacy in patients with refractory advanced non-small cell lung cancer.
Juergens RA, Wrangle J, Vendetti FP, Murphy SC, Zhao M, Coleman B, Sebree R, Rodgers K, Hooker CM, Franco N, Lee B, Tsai S, Delgado IE, Rudek MA, Belinsky SA, Herman JG, Baylin SB, Brock MV, Rudin CM. Juergens RA, et al. Among authors: lee b. Cancer Discov. 2011 Dec;1(7):598-607. doi: 10.1158/2159-8290.CD-11-0214. Epub 2011 Nov 9. Cancer Discov. 2011. PMID: 22586682 Free PMC article. Clinical Trial.
Prospective CT screening for lung cancer in a high-risk population: HIV-positive smokers.
Hulbert A, Hooker CM, Keruly JC, Brown T, Horton K, Fishman E, Rodgers K, Lee B, Sam C, Tsai S, Weihe E, Pridham G, Drummond B, Merlo C, Geronimo M, Porter M, Cox S, Li D, Harline M, Teran M, Wrangle J, Mudge B, Taylor G, Kirk GD, Herman JG, Moore RD, Brown RH, Brock MV. Hulbert A, et al. Among authors: lee b. J Thorac Oncol. 2014 Jun;9(6):752-9. doi: 10.1097/JTO.0000000000000161. J Thorac Oncol. 2014. PMID: 24828660 Free PMC article.
Comprehensive molecular profiling of lung adenocarcinoma.
Cancer Genome Atlas Research Network. Cancer Genome Atlas Research Network. Nature. 2014 Jul 31;511(7511):543-50. doi: 10.1038/nature13385. Epub 2014 Jul 9. Nature. 2014. PMID: 25079552 Free PMC article.
Early Detection of Lung Cancer Using DNA Promoter Hypermethylation in Plasma and Sputum.
Hulbert A, Jusue-Torres I, Stark A, Chen C, Rodgers K, Lee B, Griffin C, Yang A, Huang P, Wrangle J, Belinsky SA, Wang TH, Yang SC, Baylin SB, Brock MV, Herman JG. Hulbert A, et al. Among authors: lee b. Clin Cancer Res. 2017 Apr 15;23(8):1998-2005. doi: 10.1158/1078-0432.CCR-16-1371. Epub 2016 Oct 11. Clin Cancer Res. 2017. PMID: 27729459 Free PMC article.
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