Sun D - Search Results

1

Discovery of a Novel Dual-Target Inhibitor of ERK1 and ERK5 That Induces Regulated Cell Death to Overcome Compensatory Mechanism in Specific Tumor Types.

Wang G, Zhao Y, Liu Y, Sun D, Zhen Y, Liu J, Fu L, Zhang L, Ouyang L. Wang G, et al. Among authors: sun d. J Med Chem. 2020 Apr 23;63(8):3976-3995. doi: 10.1021/acs.jmedchem.9b01896. Epub 2020 Mar 5. J Med Chem. 2020. PMID: 32078308

2

Growth inhibitory effect of paratocarpin E, a prenylated chalcone isolated from Euphorbia humifusa Wild., by induction of autophagy and apoptosis in human breast cancer cells.

Gao S, Sun D, Wang G, Zhang J, Jiang Y, Li G, Zhang K, Wang L, Huang J, Chen L. Gao S, et al. Among authors: sun d. Bioorg Chem. 2016 Dec;69:121-128. doi: 10.1016/j.bioorg.2016.10.005. Epub 2016 Oct 25. Bioorg Chem. 2016. PMID: 27814565

3

A natural product from Cannabis sativa subsp. sativa inhibits homeodomain-interacting protein kinase 2 (HIPK2), attenuating MPP⁺-induced apoptosis in human neuroblastoma SH-SY5Y cells.

Wang G, Zhu L, Zhao Y, Gao S, Sun D, Yuan J, Huang Y, Zhang X, Yao X. Wang G, et al. Among authors: sun d. Bioorg Chem. 2017 Jun;72:64-73. doi: 10.1016/j.bioorg.2017.03.011. Epub 2017 Mar 30. Bioorg Chem. 2017. PMID: 28366826

4

Design, synthesis and structure-activity relationship studies of a focused library of pyrimidine moiety with anti-proliferative and anti-metastasis activities in triple negative breast cancer.

Yao D, Zhou Y, Zhu L, Ouyang L, Zhang J, Jiang Y, Zhao Y, Sun D, Yang S, Yu Y, Wang J. Yao D, et al. Among authors: sun d. Eur J Med Chem. 2017 Nov 10;140:155-171. doi: 10.1016/j.ejmech.2017.08.067. Epub 2017 Sep 20. Eur J Med Chem. 2017. PMID: 28923383

5

Fluoxetine induces autophagic cell death via eEF2K-AMPK-mTOR-ULK complex axis in triple negative breast cancer.

Sun D, Zhu L, Zhao Y, Jiang Y, Chen L, Yu Y, Ouyang L. Sun D, et al. Cell Prolif. 2018 Apr;51(2):e12402. doi: 10.1111/cpr.12402. Epub 2017 Nov 1. Cell Prolif. 2018. PMID: 29094413 Free PMC article.

6

Recent progress in potential anti-hepatitis B virus agents: Structural and pharmacological perspectives.

Sun D, Zhu L, Yao D, Chen L, Fu L, Ouyang L. Sun D, et al. Eur J Med Chem. 2018 Mar 10;147:205-217. doi: 10.1016/j.ejmech.2018.02.001. Epub 2018 Feb 5. Eur J Med Chem. 2018. PMID: 29438889 Review.

7

Dual-target kinase drug design: Current strategies and future directions in cancer therapy.

Sun D, Zhao Y, Zhang S, Zhang L, Liu B, Ouyang L. Sun D, et al. Eur J Med Chem. 2020 Feb 15;188:112025. doi: 10.1016/j.ejmech.2019.112025. Epub 2020 Jan 2. Eur J Med Chem. 2020. PMID: 31931340 Review.

8

Diarylheptanoid: A privileged structure in drug discovery.

Sun DJ, Zhu LJ, Zhao YQ, Zhen YQ, Zhang L, Lin CC, Chen LX. Sun DJ, et al. Fitoterapia. 2020 Apr;142:104490. doi: 10.1016/j.fitote.2020.104490. Epub 2020 Feb 1. Fitoterapia. 2020. PMID: 32017968 Review.

9

Targeting mTOR for fighting diseases: A revisited review of mTOR inhibitors.

Xu T, Sun D, Chen Y, Ouyang L. Xu T, et al. Among authors: sun d. Eur J Med Chem. 2020 Aug 1;199:112391. doi: 10.1016/j.ejmech.2020.112391. Epub 2020 May 4. Eur J Med Chem. 2020. PMID: 32416459 Review.

10

Si-Miao-Yong-An Decoction attenuates isoprenaline-induced myocardial fibrosis in AMPK-driven Akt/mTOR and TGF-β/SMAD3 pathways.

Zhao Y, Sun D, Chen Y, Zhan K, Meng Q, Zhang X, Zhu L, Yao X. Zhao Y, et al. Among authors: sun d. Biomed Pharmacother. 2020 Oct;130:110522. doi: 10.1016/j.biopha.2020.110522. Epub 2020 Jul 28. Biomed Pharmacother. 2020. PMID: 32736236 Free article.

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