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Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson's Disease.
Sampson TR, Debelius JW, Thron T, Janssen S, Shastri GG, Ilhan ZE, Challis C, Schretter CE, Rocha S, Gradinaru V, Chesselet MF, Keshavarzian A, Shannon KM, Krajmalnik-Brown R, Wittung-Stafshede P, Knight R, Mazmanian SK. Sampson TR, et al. Among authors: gradinaru v. Cell. 2016 Dec 1;167(6):1469-1480.e12. doi: 10.1016/j.cell.2016.11.018. Cell. 2016. PMID: 27912057 Free PMC article.
Systemic AAV vectors for widespread and targeted gene delivery in rodents.
Challis RC, Ravindra Kumar S, Chan KY, Challis C, Beadle K, Jang MJ, Kim HM, Rajendran PS, Tompkins JD, Shivkumar K, Deverman BE, Gradinaru V. Challis RC, et al. Among authors: gradinaru v. Nat Protoc. 2019 Feb;14(2):379-414. doi: 10.1038/s41596-018-0097-3. Nat Protoc. 2019. PMID: 30626963
Identification of peripheral neural circuits that regulate heart rate using optogenetic and viral vector strategies.
Rajendran PS, Challis RC, Fowlkes CC, Hanna P, Tompkins JD, Jordan MC, Hiyari S, Gabris-Weber BA, Greenbaum A, Chan KY, Deverman BE, Münzberg H, Ardell JL, Salama G, Gradinaru V, Shivkumar K. Rajendran PS, et al. Among authors: gradinaru v. Nat Commun. 2019 Apr 26;10(1):1944. doi: 10.1038/s41467-019-09770-1. Nat Commun. 2019. PMID: 31028266 Free PMC article.
A gut bacterial amyloid promotes α-synuclein aggregation and motor impairment in mice.
Sampson TR, Challis C, Jain N, Moiseyenko A, Ladinsky MS, Shastri GG, Thron T, Needham BD, Horvath I, Debelius JW, Janssen S, Knight R, Wittung-Stafshede P, Gradinaru V, Chapman M, Mazmanian SK. Sampson TR, et al. Among authors: gradinaru v. Elife. 2020 Feb 11;9:e53111. doi: 10.7554/eLife.53111. Elife. 2020. PMID: 32043464 Free PMC article.
169 results