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Allele-specific expression changes dynamically during T cell activation in HLA and other autoimmune loci.
Gutierrez-Arcelus M, Baglaenko Y, Arora J, Hannes S, Luo Y, Amariuta T, Teslovich N, Rao DA, Ermann J, Jonsson AH; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; Navarrete C, Rich SS, Taylor KD, Rotter JI, Gregersen PK, Esko T, Brenner MB, Raychaudhuri S. Gutierrez-Arcelus M, et al. Among authors: rotter ji. Nat Genet. 2020 Mar;52(3):247-253. doi: 10.1038/s41588-020-0579-4. Epub 2020 Feb 17. Nat Genet. 2020. PMID: 32066938 Free PMC article.
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis.
Rioux JD, Xavier RJ, Taylor KD, Silverberg MS, Goyette P, Huett A, Green T, Kuballa P, Barmada MM, Datta LW, Shugart YY, Griffiths AM, Targan SR, Ippoliti AF, Bernard EJ, Mei L, Nicolae DL, Regueiro M, Schumm LP, Steinhart AH, Rotter JI, Duerr RH, Cho JH, Daly MJ, Brant SR. Rioux JD, et al. Among authors: rotter ji. Nat Genet. 2007 May;39(5):596-604. doi: 10.1038/ng2032. Epub 2007 Apr 15. Nat Genet. 2007. PMID: 17435756 Free PMC article.
TNFSF15 is an ethnic-specific IBD gene.
Picornell Y, Mei L, Taylor K, Yang H, Targan SR, Rotter JI. Picornell Y, et al. Among authors: rotter ji. Inflamm Bowel Dis. 2007 Nov;13(11):1333-8. doi: 10.1002/ibd.20223. Inflamm Bowel Dis. 2007. PMID: 17663424 Free PMC article.
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.
Barrett JC, Hansoul S, Nicolae DL, Cho JH, Duerr RH, Rioux JD, Brant SR, Silverberg MS, Taylor KD, Barmada MM, Bitton A, Dassopoulos T, Datta LW, Green T, Griffiths AM, Kistner EO, Murtha MT, Regueiro MD, Rotter JI, Schumm LP, Steinhart AH, Targan SR, Xavier RJ; NIDDK IBD Genetics Consortium; Libioulle C, Sandor C, Lathrop M, Belaiche J, Dewit O, Gut I, Heath S, Laukens D, Mni M, Rutgeerts P, Van Gossum A, Zelenika D, Franchimont D, Hugot JP, de Vos M, Vermeire S, Louis E; Belgian-French IBD Consortium; Wellcome Trust Case Control Consortium; Cardon LR, Anderson CA, Drummond H, Nimmo E, Ahmad T, Prescott NJ, Onnie CM, Fisher SA, Marchini J, Ghori J, Bumpstead S, Gwilliam R, Tremelling M, Deloukas P, Mansfield J, Jewell D, Satsangi J, Mathew CG, Parkes M, Georges M, Daly MJ. Barrett JC, et al. Among authors: rotter ji. Nat Genet. 2008 Aug;40(8):955-62. doi: 10.1038/ng.175. Epub 2008 Jun 29. Nat Genet. 2008. PMID: 18587394 Free PMC article.
1,236 results