Alemany R - Search Results

1

First-in-Human, First-in-Child Trial of Autologous MSCs Carrying the Oncolytic Virus Icovir-5 in Patients with Advanced Tumors.

Ruano D, López-Martín JA, Moreno L, Lassaletta Á, Bautista F, Andión M, Hernández C, González-Murillo Á, Melen G, Alemany R, Madero L, García-Castro J, Ramírez M. Ruano D, et al. Among authors: alemany r. Mol Ther. 2020 Apr 8;28(4):1033-1042. doi: 10.1016/j.ymthe.2020.01.019. Epub 2020 Jan 21. Mol Ther. 2020. PMID: 32053771 Free PMC article. Clinical Trial.

2

Tumor cells as cellular vehicles to deliver gene therapies to metastatic tumors.

García-Castro J, Martínez-Palacio J, Lillo R, García-Sánchez F, Alemany R, Madero L, Bueren JA, Ramírez M. García-Castro J, et al. Among authors: alemany r. Cancer Gene Ther. 2005 Apr;12(4):341-9. doi: 10.1038/sj.cgt.7700801. Cancer Gene Ther. 2005. PMID: 15650763

3

Deletion of VAI and VAII RNA genes in the design of oncolytic adenoviruses.

Cascallo M, Gros A, Bayo N, Serrano T, Capella G, Alemany R. Cascallo M, et al. Among authors: alemany r. Hum Gene Ther. 2006 Sep;17(9):929-40. doi: 10.1089/hum.2006.17.929. Hum Gene Ther. 2006. PMID: 16972761

4

Systemic toxicity-efficacy profile of ICOVIR-5, a potent and selective oncolytic adenovirus based on the pRB pathway.

Cascallo M, Alonso MM, Rojas JJ, Perez-Gimenez A, Fueyo J, Alemany R. Cascallo M, et al. Among authors: alemany r. Mol Ther. 2007 Sep;15(9):1607-15. doi: 10.1038/sj.mt.6300239. Epub 2007 Jun 19. Mol Ther. 2007. PMID: 17579575 Free article.

5

Syncytia formation affects the yield and cytotoxicity of an adenovirus expressing a fusogenic glycoprotein at a late stage of replication.

Guedan S, Gros A, Cascallo M, Vile R, Mercade E, Alemany R. Guedan S, et al. Among authors: alemany r. Gene Ther. 2008 Sep;15(17):1240-5. doi: 10.1038/gt.2008.94. Epub 2008 May 29. Gene Ther. 2008. PMID: 18509378 Free PMC article.

6

A modified E2F-1 promoter improves the efficacy to toxicity ratio of oncolytic adenoviruses.

Rojas JJ, Cascallo M, Guedan S, Gros A, Martinez-Quintanilla J, Hemminki A, Alemany R. Rojas JJ, et al. Among authors: alemany r. Gene Ther. 2009 Dec;16(12):1441-51. doi: 10.1038/gt.2009.103. Gene Ther. 2009. PMID: 19710704

7

Treatment of metastatic neuroblastoma with systemic oncolytic virotherapy delivered by autologous mesenchymal stem cells: an exploratory study.

García-Castro J, Alemany R, Cascalló M, Martínez-Quintanilla J, Arriero Mdel M, Lassaletta A, Madero L, Ramírez M. García-Castro J, et al. Among authors: alemany r. Cancer Gene Ther. 2010 Jul;17(7):476-83. doi: 10.1038/cgt.2010.4. Epub 2010 Feb 19. Cancer Gene Ther. 2010. PMID: 20168350

8

Verapamil enhances the antitumoral efficacy of oncolytic adenoviruses.

Gros A, Puig C, Guedan S, Rojas JJ, Alemany R, Cascallo M. Gros A, et al. Among authors: alemany r. Mol Ther. 2010 May;18(5):903-11. doi: 10.1038/mt.2010.22. Epub 2010 Feb 23. Mol Ther. 2010. PMID: 20179683 Free PMC article.

9

Hyaluronidase expression by an oncolytic adenovirus enhances its intratumoral spread and suppresses tumor growth.

Guedan S, Rojas JJ, Gros A, Mercade E, Cascallo M, Alemany R. Guedan S, et al. Among authors: alemany r. Mol Ther. 2010 Jul;18(7):1275-83. doi: 10.1038/mt.2010.79. Epub 2010 May 4. Mol Ther. 2010. PMID: 20442708 Free PMC article.

10

Osteosarcoma cells as carriers to allow antitumor activity of canine oncolytic adenovirus in the presence of neutralizing antibodies.

Alcayaga-Miranda F, Cascallo M, Rojas JJ, Pastor J, Alemany R. Alcayaga-Miranda F, et al. Among authors: alemany r. Cancer Gene Ther. 2010 Nov;17(11):792-802. doi: 10.1038/cgt.2010.36. Epub 2010 Jul 30. Cancer Gene Ther. 2010. PMID: 20671769

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