Zhen YQ - Search Results

1

Diarylheptanoid: A privileged structure in drug discovery.

Sun DJ, Zhu LJ, Zhao YQ, Zhen YQ, Zhang L, Lin CC, Chen LX. Sun DJ, et al. Among authors: zhen yq. Fitoterapia. 2020 Apr;142:104490. doi: 10.1016/j.fitote.2020.104490. Epub 2020 Feb 1. Fitoterapia. 2020. PMID: 32017968 Review.

2

Design, synthesis and biological evaluation of benzamide derivatives as novel NTCP inhibitors that induce apoptosis in HepG2 cells.

Zhao S, Zhen Y, Fu L, Gao F, Zhou X, Huang S, Zhang L. Zhao S, et al. Bioorg Med Chem Lett. 2019 Oct 1;29(19):126623. doi: 10.1016/j.bmcl.2019.126623. Epub 2019 Aug 14. Bioorg Med Chem Lett. 2019. PMID: 31439379

3

Discovery of a Novel Dual-Target Inhibitor of ERK1 and ERK5 That Induces Regulated Cell Death to Overcome Compensatory Mechanism in Specific Tumor Types.

Wang G, Zhao Y, Liu Y, Sun D, Zhen Y, Liu J, Fu L, Zhang L, Ouyang L. Wang G, et al. J Med Chem. 2020 Apr 23;63(8):3976-3995. doi: 10.1021/acs.jmedchem.9b01896. Epub 2020 Mar 5. J Med Chem. 2020. PMID: 32078308

4

Flubendazole elicits anti-cancer effects via targeting EVA1A-modulated autophagy and apoptosis in Triple-negative Breast Cancer.

Zhen Y, Zhao R, Wang M, Jiang X, Gao F, Fu L, Zhang L, Zhou XL. Zhen Y, et al. Theranostics. 2020 Jul 2;10(18):8080-8097. doi: 10.7150/thno.43473. eCollection 2020. Theranostics. 2020. PMID: 32724459 Free PMC article.

5

Discovery of 5-bromo-4-phenoxy-N-phenylpyrimidin-2-amine derivatives as novel ULK1 inhibitors that block autophagy and induce apoptosis in non-small cell lung cancer.

Sun D, Yang Z, Zhen Y, Yang Y, Chen Y, Yuan Y, Zhang L, Zeng X, Chen L. Sun D, et al. Eur J Med Chem. 2020 Dec 15;208:112782. doi: 10.1016/j.ejmech.2020.112782. Epub 2020 Aug 29. Eur J Med Chem. 2020. PMID: 32961380

6

Isolation, Structure Elucidation, Semi-Synthesis, and Structural Modification of C₁₉-Diterpenoid Alkaloids from Aconitum apetalum and Their Neuroprotective Activities.

Wan LX, Zhang JF, Zhen YQ, Zhang L, Li X, Gao F, Zhou XL. Wan LX, et al. Among authors: zhen yq. J Nat Prod. 2021 Apr 23;84(4):1067-1077. doi: 10.1021/acs.jnatprod.0c01111. Epub 2021 Mar 5. J Nat Prod. 2021. PMID: 33666437

7

Late-Stage Modification of Medicine: Pd-Catalyzed Direct Synthesis and Biological Evaluation of N-Aryltacrine Derivatives.

Wan LX, Zhen YQ, He ZX, Zhang Y, Zhang L, Li X, Gao F, Zhou XL. Wan LX, et al. Among authors: zhen yq. ACS Omega. 2021 Apr 2;6(14):9960-9972. doi: 10.1021/acsomega.1c01404. eCollection 2021 Apr 13. ACS Omega. 2021. PMID: 33869976 Free PMC article.

8

Repurposing non-oncology small-molecule drugs to improve cancer therapy: Current situation and future directions.

Fu L, Jin W, Zhang J, Zhu L, Lu J, Zhen Y, Zhang L, Ouyang L, Liu B, Yu H. Fu L, et al. Acta Pharm Sin B. 2022 Feb;12(2):532-557. doi: 10.1016/j.apsb.2021.09.006. Epub 2021 Sep 10. Acta Pharm Sin B. 2022. PMID: 35256933 Free PMC article. Review.

9

Flubendazole induces mitochondrial dysfunction and DRP1-mediated mitophagy by targeting EVA1A in breast cancer.

Zhen Y, Yuan Z, Zhang J, Chen Y, Fu Y, Liu Y, Fu L, Zhang L, Zhou XL. Zhen Y, et al. Cell Death Dis. 2022 Apr 19;13(4):375. doi: 10.1038/s41419-022-04823-8. Cell Death Dis. 2022. PMID: 35440104 Free PMC article.

10

Deep Learning Promotes the Screening of Natural Products with Potential Microtubule Inhibition Activity.

Jia XN, Wang WJ, Yin B, Zhou LJ, Zhen YQ, Zhang L, Zhou XL, Song HN, Tang Y, Gao F. Jia XN, et al. Among authors: zhen yq. ACS Omega. 2022 Aug 5;7(32):28334-28341. doi: 10.1021/acsomega.2c02854. eCollection 2022 Aug 16. ACS Omega. 2022. PMID: 35990425 Free PMC article.

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