Kelch BA - Search Results

1

A thermophilic phage uses a small terminase protein with a fixed helix-turn-helix geometry.

Hayes JA, Hilbert BJ, Gaubitz C, Stone NP, Kelch BA. Hayes JA, et al. Among authors: kelch ba. J Biol Chem. 2020 Mar 20;295(12):3783-3793. doi: 10.1074/jbc.RA119.012224. Epub 2020 Feb 3. J Biol Chem. 2020. PMID: 32014998 Free PMC article.

2

Structure and mechanism of the ATPase that powers viral genome packaging.

Hilbert BJ, Hayes JA, Stone NP, Duffy CM, Sankaran B, Kelch BA. Hilbert BJ, et al. Among authors: kelch ba. Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):E3792-9. doi: 10.1073/pnas.1506951112. Epub 2015 Jul 6. Proc Natl Acad Sci U S A. 2015. PMID: 26150523 Free PMC article.

3

A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site.

Duffy CM, Hilbert BJ, Kelch BA. Duffy CM, et al. Among authors: kelch ba. J Mol Biol. 2016 Mar 27;428(6):1023-1040. doi: 10.1016/j.jmb.2015.11.029. Epub 2015 Dec 11. J Mol Biol. 2016. PMID: 26688547

4

The large terminase DNA packaging motor grips DNA with its ATPase domain for cleavage by the flexible nuclease domain.

Hilbert BJ, Hayes JA, Stone NP, Xu RG, Kelch BA. Hilbert BJ, et al. Among authors: kelch ba. Nucleic Acids Res. 2017 Apr 7;45(6):3591-3605. doi: 10.1093/nar/gkw1356. Nucleic Acids Res. 2017. PMID: 28082398 Free PMC article.

5

Crystal structure of APOBEC3A bound to single-stranded DNA reveals structural basis for cytidine deamination and specificity.

Kouno T, Silvas TV, Hilbert BJ, Shandilya SMD, Bohn MF, Kelch BA, Royer WE, Somasundaran M, Kurt Yilmaz N, Matsuo H, Schiffer CA. Kouno T, et al. Among authors: kelch ba. Nat Commun. 2017 Apr 28;8:15024. doi: 10.1038/ncomms15024. Nat Commun. 2017. PMID: 28452355 Free PMC article.

6

A Hyperthermophilic Phage Decoration Protein Suggests Common Evolutionary Origin with Herpesvirus Triplex Proteins and an Anti-CRISPR Protein.

Stone NP, Hilbert BJ, Hidalgo D, Halloran KT, Lee J, Sontheimer EJ, Kelch BA. Stone NP, et al. Among authors: kelch ba. Structure. 2018 Jul 3;26(7):936-947.e3. doi: 10.1016/j.str.2018.04.008. Epub 2018 May 17. Structure. 2018. PMID: 29779790 Free PMC article.

7

Effective mismatch repair depends on timely control of PCNA retention on DNA by the Elg1 complex.

Paul Solomon Devakumar LJ, Gaubitz C, Lundblad V, Kelch BA, Kubota T. Paul Solomon Devakumar LJ, et al. Among authors: kelch ba. Nucleic Acids Res. 2019 Jul 26;47(13):6826-6841. doi: 10.1093/nar/gkz441. Nucleic Acids Res. 2019. PMID: 31114918 Free PMC article.

8

Principles for enhancing virus capsid capacity and stability from a thermophilic virus capsid structure.

Stone NP, Demo G, Agnello E, Kelch BA. Stone NP, et al. Among authors: kelch ba. Nat Commun. 2019 Oct 2;10(1):4471. doi: 10.1038/s41467-019-12341-z. Nat Commun. 2019. PMID: 31578335 Free PMC article.

9

Structure of the human clamp loader reveals an autoinhibited conformation of a substrate-bound AAA+ switch.

Gaubitz C, Liu X, Magrino J, Stone NP, Landeck J, Hedglin M, Kelch BA. Gaubitz C, et al. Among authors: kelch ba. Proc Natl Acad Sci U S A. 2020 Sep 22;117(38):23571-23580. doi: 10.1073/pnas.2007437117. Epub 2020 Sep 9. Proc Natl Acad Sci U S A. 2020. PMID: 32907938 Free PMC article.

10

Viral packaging ATPases utilize a glutamate switch to couple ATPase activity and DNA translocation.

Pajak J, Atz R, Hilbert BJ, Morais MC, Kelch BA, Jardine PJ, Arya G. Pajak J, et al. Among authors: kelch ba. Proc Natl Acad Sci U S A. 2021 Apr 27;118(17):e2024928118. doi: 10.1073/pnas.2024928118. Proc Natl Acad Sci U S A. 2021. PMID: 33888587 Free PMC article.

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