Mitochondrial DNA copy number can influence mortality and cardiovascular disease via methylation of nuclear DNA CpGs.
Castellani CA, Longchamps RJ, Sumpter JA, Newcomb CE, Lane JA, Grove ML, Bressler J, Brody JA, Floyd JS, Bartz TM, Taylor KD, Wang P, Tin A, Coresh J, Pankow JS, Fornage M, Guallar E, O'Rourke B, Pankratz N, Liu C, Levy D, Sotoodehnia N, Boerwinkle E, Arking DE.
Castellani CA, et al. Among authors: newcomb ce.
Genome Med. 2020 Sep 28;12(1):84. doi: 10.1186/s13073-020-00778-7.
Genome Med. 2020.
PMID: 32988399
Free PMC article.