Siddiqui FA - Search Results

1

PDE6D Inhibitors with a New Design Principle Selectively Block K-Ras Activity.

Siddiqui FA, Alam C, Rosenqvist P, Ora M, Sabt A, Manoharan GB, Bindu L, Okutachi S, Catillon M, Taylor T, Abdelhafez OM, Lönnberg H, Stephen AG, Papageorgiou AC, Virta P, Abankwa D. Siddiqui FA, et al. ACS Omega. 2019 Dec 23;5(1):832-842. doi: 10.1021/acsomega.9b03639. eCollection 2020 Jan 14. ACS Omega. 2019. PMID: 31956834 Free PMC article.

2

Medium-Throughput Detection of Hsp90/Cdc37 Protein-Protein Interaction Inhibitors Using a Split Renilla Luciferase-Based Assay.

Siddiqui FA, Parkkola H, Manoharan GB, Abankwa D. Siddiqui FA, et al. SLAS Discov. 2020 Feb;25(2):195-206. doi: 10.1177/2472555219884033. Epub 2019 Oct 29. SLAS Discov. 2020. PMID: 31662027 Free article.

3

Elaiophylin Is a Potent Hsp90/ Cdc37 Protein Interface Inhibitor with K-Ras Nanocluster Selectivity.

Siddiqui FA, Vukic V, Salminen TA, Abankwa D. Siddiqui FA, et al. Biomolecules. 2021 Jun 4;11(6):836. doi: 10.3390/biom11060836. Biomolecules. 2021. PMID: 34199986 Free PMC article.

4

NRAS is unique among RAS proteins in requiring ICMT for trafficking to the plasma membrane.

Ahearn IM, Court HR, Siddiqui F, Abankwa D, Philips MR. Ahearn IM, et al. Life Sci Alliance. 2021 Feb 12;4(5):e202000972. doi: 10.26508/lsa.202000972. Print 2021 May. Life Sci Alliance. 2021. PMID: 33579760 Free PMC article.

5

Novel Small Molecule Hsp90/Cdc37 Interface Inhibitors Indirectly Target K-Ras-Signaling.

Siddiqui FA, Parkkola H, Vukic V, Oetken-Lindholm C, Jaiswal A, Kiriazis A, Pavic K, Aittokallio T, Salminen TA, Abankwa D. Siddiqui FA, et al. Cancers (Basel). 2021 Feb 23;13(4):927. doi: 10.3390/cancers13040927. Cancers (Basel). 2021. PMID: 33672199 Free PMC article.

6

FLIM-FRET Analysis of Ras Nanoclustering and Membrane-Anchorage.

Parkkola H, Siddiqui FA, Oetken-Lindholm C, Abankwa D. Parkkola H, et al. Among authors: siddiqui fa. Methods Mol Biol. 2021;2262:233-250. doi: 10.1007/978-1-0716-1190-6_13. Methods Mol Biol. 2021. PMID: 33977480

7

Opposite feedback from mTORC1 to H-ras and K-ras4B downstream of SREBP1.

Posada IMD, Lectez B, Siddiqui FA, Oetken-Lindholm C, Sharma M, Abankwa D. Posada IMD, et al. Among authors: siddiqui fa. Sci Rep. 2017 Aug 21;7(1):8944. doi: 10.1038/s41598-017-09387-8. Sci Rep. 2017. PMID: 28827765 Free PMC article.

8

A subset of flavaglines inhibits KRAS nanoclustering and activation.

Yurugi H, Zhuang Y, Siddiqui FA, Liang H, Rosigkeit S, Zeng Y, Abou-Hamdan H, Bockamp E, Zhou Y, Abankwa D, Zhao W, Désaubry L, Rajalingam K. Yurugi H, et al. Among authors: siddiqui fa. J Cell Sci. 2020 Jun 24;133(12):jcs244111. doi: 10.1242/jcs.244111. J Cell Sci. 2020. PMID: 32501281

9

[No title available]

[No authors listed] [No authors listed] PMID: 34005204

10

Curcumin decreases Warburg effect in cancer cells by down-regulating pyruvate kinase M2 via mTOR-HIF1α inhibition.

Siddiqui FA, Prakasam G, Chattopadhyay S, Rehman AU, Padder RA, Ansari MA, Irshad R, Mangalhara K, Bamezai RNK, Husain M, Ali SM, Iqbal MA. Siddiqui FA, et al. Sci Rep. 2018 May 29;8(1):8323. doi: 10.1038/s41598-018-25524-3. Sci Rep. 2018. PMID: 29844464 Free PMC article.

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