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Host-mediated ubiquitination of a mycobacterial protein suppresses immunity.
Wang L, Wu J, Li J, Yang H, Tang T, Liang H, Zuo M, Wang J, Liu H, Liu F, Chen J, Liu Z, Wang Y, Peng C, Wu X, Zheng R, Huang X, Ran Y, Rao Z, Ge B. Wang L, et al. Among authors: wu x, wu j. Nature. 2020 Jan;577(7792):682-688. doi: 10.1038/s41586-019-1915-7. Epub 2020 Jan 15. Nature. 2020. PMID: 31942069
Nuclear cGAS suppresses DNA repair and promotes tumorigenesis.
Liu H, Zhang H, Wu X, Ma D, Wu J, Wang L, Jiang Y, Fei Y, Zhu C, Tan R, Jungblut P, Pei G, Dorhoi A, Yan Q, Zhang F, Zheng R, Liu S, Liang H, Liu Z, Yang H, Chen J, Wang P, Tang T, Peng W, Hu Z, Xu Z, Huang X, Wang J, Li H, Zhou Y, Liu F, Yan D, Kaufmann SHE, Chen C, Mao Z, Ge B. Liu H, et al. Among authors: wu x, wu j. Nature. 2018 Nov;563(7729):131-136. doi: 10.1038/s41586-018-0629-6. Epub 2018 Oct 24. Nature. 2018. PMID: 30356214
Oxidization of TGFβ-activated kinase by MPT53 is required for immunity to Mycobacterium tuberculosis.
Wang L, Liu Z, Wang J, Liu H, Wu J, Tang T, Li H, Yang H, Qin L, Ma D, Chen J, Liu F, Wang P, Zheng R, Song P, Zhou Y, Cui Z, Wu X, Huang X, Liang H, Zhang S, Cao J, Wu C, Chen Y, Su D, Chen X, Zeng G, Ge B. Wang L, et al. Among authors: wu x, wu c, wu j. Nat Microbiol. 2019 Aug;4(8):1378-1388. doi: 10.1038/s41564-019-0436-3. Epub 2019 May 20. Nat Microbiol. 2019. PMID: 31110366
Genome-wide association study identifies two risk loci for tuberculosis in Han Chinese.
Zheng R, Li Z, He F, Liu H, Chen J, Chen J, Xie X, Zhou J, Chen H, Wu X, Wu J, Chen B, Liu Y, Cui H, Fan L, Sha W, Liu Y, Wang J, Huang X, Zhang L, Xu F, Wang J, Feng Y, Qin L, Yang H, Liu Z, Cui Z, Liu F, Chen X, Gao S, Sun S, Shi Y, Ge B. Zheng R, et al. Among authors: wu x, wu j. Nat Commun. 2018 Oct 4;9(1):4072. doi: 10.1038/s41467-018-06539-w. Nat Commun. 2018. PMID: 30287856 Free PMC article.
CGAS is a micronucleophagy receptor for the clearance of micronuclei.
Zhao M, Wang F, Wu J, Cheng Y, Cao Y, Wu X, Ma M, Tang F, Liu Z, Liu H, Ge B. Zhao M, et al. Among authors: wu x, wu j. Autophagy. 2021 Dec;17(12):3976-3991. doi: 10.1080/15548627.2021.1899440. Epub 2021 Mar 22. Autophagy. 2021. PMID: 33752561 Free PMC article.
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