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The LC3-conjugation machinery specifies the loading of RNA-binding proteins into extracellular vesicles.
Leidal AM, Huang HH, Marsh T, Solvik T, Zhang D, Ye J, Kai F, Goldsmith J, Liu JY, Huang YH, Monkkonen T, Vlahakis A, Huang EJ, Goodarzi H, Yu L, Wiita AP, Debnath J. Leidal AM, et al. Among authors: wiita ap. Nat Cell Biol. 2020 Feb;22(2):187-199. doi: 10.1038/s41556-019-0450-y. Epub 2020 Jan 13. Nat Cell Biol. 2020. PMID: 31932738 Free PMC article.
Cell-Type Specificity of Mosaic Chromosome 1q Gain Resolved by snRNA-seq in a Case of Epilepsy With Hyaline Protoplasmic Astrocytopathy.
Leng K, Cadwell CR, Devine WP, Tihan T, Qi Z, Singhal NS, Glenn OA, Kamiya S, Wiita AP, Berger AC, Shieh JT, Titus EW, Paredes MF, Upadhyay V. Leng K, et al. Among authors: wiita ap. Neurol Genet. 2024 Apr 3;10(2):e200142. doi: 10.1212/NXG.0000000000200142. eCollection 2024 Apr. Neurol Genet. 2024. PMID: 38586598 Free PMC article.
Challenges in the discovery of tumor-specific alternative splicing-derived cell-surface antigens in glioma.
Nejo T, Wang L, Leung KK, Wang A, Lakshmanachetty S, Gallus M, Kwok DW, Hong C, Chen LH, Carrera DA, Zhang MY, Stevers NO, Maldonado GC, Yamamichi A, Watchmaker P, Naik A, Shai A, Phillips JJ, Chang SM, Wiita AP, Wells JA, Costello JF, Diaz AA, Okada H. Nejo T, et al. Among authors: wiita ap. bioRxiv [Preprint]. 2023 Nov 2:2023.10.26.564156. doi: 10.1101/2023.10.26.564156. bioRxiv. 2023. Update in: Sci Rep. 2024 Mar 16;14(1):6362. doi: 10.1038/s41598-024-56684-0. PMID: 37961484 Free PMC article. Updated. Preprint.
Proteasome inhibitor-induced modulation reveals the spliceosome as a specific therapeutic vulnerability in multiple myeloma.
Huang HH, Ferguson ID, Thornton AM, Bastola P, Lam C, Lin YT, Choudhry P, Mariano MC, Marcoulis MD, Teo CF, Malato J, Phojanakong PJ, Martin TG 3rd, Wolf JL, Wong SW, Shah N, Hann B, Brooks AN, Wiita AP. Huang HH, et al. Among authors: wiita ap. Nat Commun. 2020 Apr 22;11(1):1931. doi: 10.1038/s41467-020-15521-4. Nat Commun. 2020. PMID: 32321912 Free PMC article.
Secretory autophagy maintains proteostasis upon lysosome inhibition.
Solvik TA, Nguyen TA, Tony Lin YH, Marsh T, Huang EJ, Wiita AP, Debnath J, Leidal AM. Solvik TA, et al. Among authors: wiita ap. J Cell Biol. 2022 Jun 6;221(6):e202110151. doi: 10.1083/jcb.202110151. Epub 2022 Apr 21. J Cell Biol. 2022. PMID: 35446347 Free PMC article.
ECM dimensionality tunes actin tension to modulate endoplasmic reticulum function and spheroid phenotypes of mammary epithelial cells.
Kai F, Ou G, Tourdot RW, Stashko C, Gaietta G, Swift MF, Volkmann N, Long AF, Han Y, Huang HH, Northey JJ, Leidal AM, Viasnoff V, Bryant DM, Guo W, Wiita AP, Guo M, Dumont S, Hanein D, Radhakrishnan R, Weaver VM. Kai F, et al. Among authors: wiita ap. EMBO J. 2022 Sep 1;41(17):e109205. doi: 10.15252/embj.2021109205. Epub 2022 Jul 25. EMBO J. 2022. PMID: 35880301 Free PMC article.
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