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Peptide-TLR-7/8a conjugate vaccines chemically programmed for nanoparticle self-assembly enhance CD8 T-cell immunity to tumor antigens.
Lynn GM, Sedlik C, Baharom F, Zhu Y, Ramirez-Valdez RA, Coble VL, Tobin K, Nichols SR, Itzkowitz Y, Zaidi N, Gammon JM, Blobel NJ, Denizeau J, de la Rochere P, Francica BJ, Decker B, Maciejewski M, Cheung J, Yamane H, Smelkinson MG, Francica JR, Laga R, Bernstock JD, Seymour LW, Drake CG, Jewell CM, Lantz O, Piaggio E, Ishizuka AS, Seder RA. Lynn GM, et al. Among authors: yamane h. Nat Biotechnol. 2020 Mar;38(3):320-332. doi: 10.1038/s41587-019-0390-x. Epub 2020 Jan 13. Nat Biotechnol. 2020. PMID: 31932728 Free PMC article.
Intravenous nanoparticle vaccination generates stem-like TCF1+ neoantigen-specific CD8+ T cells.
Baharom F, Ramirez-Valdez RA, Tobin KKS, Yamane H, Dutertre CA, Khalilnezhad A, Reynoso GV, Coble VL, Lynn GM, Mulè MP, Martins AJ, Finnigan JP, Zhang XM, Hamerman JA, Bhardwaj N, Tsang JS, Hickman HD, Ginhoux F, Ishizuka AS, Seder RA. Baharom F, et al. Among authors: yamane h. Nat Immunol. 2021 Jan;22(1):41-52. doi: 10.1038/s41590-020-00810-3. Epub 2020 Nov 2. Nat Immunol. 2021. PMID: 33139915 Free PMC article.
Differentiation of effector CD4 T cell populations (*).
Zhu J, Yamane H, Paul WE. Zhu J, et al. Among authors: yamane h. Annu Rev Immunol. 2010;28:445-89. doi: 10.1146/annurev-immunol-030409-101212. Annu Rev Immunol. 2010. PMID: 20192806 Free PMC article. Review.
Generation of antitumor chimeric antigen receptors incorporating T cell signaling motifs.
Balagopalan L, Moreno T, Qin H, Angeles BC, Kondo T, Yi J, McIntire KM, Alvinez N, Pallikkuth S, Lee ME, Yamane H, Tran AD, Youkharibache P, Cachau RE, Taylor N, Samelson LE. Balagopalan L, et al. Among authors: yamane h. Sci Signal. 2024 Jul 23;17(846):eadp8569. doi: 10.1126/scisignal.adp8569. Epub 2024 Jul 23. Sci Signal. 2024. PMID: 39042728 Free PMC article.
840 results