Parker A - Search Results

1

Modification of an aggressive model of Alport Syndrome reveals early differences in disease pathogenesis due to genetic background.

Falcone S, Wisby L, Nicol T, Blease A, Starbuck B, Parker A, Sanderson J, Brown SDM, Scudamore CL, Pusey CD, Tam FWK, Potter PK. Falcone S, et al. Among authors: parker a. Sci Rep. 2019 Dec 31;9(1):20398. doi: 10.1038/s41598-019-56837-6. Sci Rep. 2019. PMID: 31892712 Free PMC article.

2

Gene-environment interactions differentially affect mouse strain behavioral parameters.

Tucci V, Lad HV, Parker A, Polley S, Brown SD, Nolan PM. Tucci V, et al. Among authors: parker a. Mamm Genome. 2006 Nov;17(11):1113-20. doi: 10.1007/s00335-006-0075-x. Epub 2006 Nov 7. Mamm Genome. 2006. PMID: 17091318

3

Analysis of the mouse mutant Cloth-ears shows a role for the voltage-gated sodium channel Scn8a in peripheral neural hearing loss.

Mackenzie FE, Parker A, Parkinson NJ, Oliver PL, Brooker D, Underhill P, Lukashkina VA, Lukashkin AN, Holmes C, Brown SD. Mackenzie FE, et al. Among authors: parker a. Genes Brain Behav. 2009 Oct;8(7):699-713. doi: 10.1111/j.1601-183X.2009.00514.x. Epub 2009 Jun 22. Genes Brain Behav. 2009. PMID: 19737145 Free PMC article.

4

A hearing and vestibular phenotyping pipeline to identify mouse mutants with hearing impairment.

Hardisty-Hughes RE, Parker A, Brown SD. Hardisty-Hughes RE, et al. Among authors: parker a. Nat Protoc. 2010 Jan;5(1):177-90. doi: 10.1038/nprot.2009.204. Epub 2010 Jan 7. Nat Protoc. 2010. PMID: 20057387

5

Gelsolin plays a role in the actin polymerization complex of hair cell stereocilia.

Mburu P, Romero MR, Hilton H, Parker A, Townsend S, Kikkawa Y, Brown SD. Mburu P, et al. Among authors: parker a. PLoS One. 2010 Jul 16;5(7):e11627. doi: 10.1371/journal.pone.0011627. PLoS One. 2010. PMID: 20661277 Free PMC article.

6

Melody, an ENU mutation in Caspase 3, alters the catalytic cysteine residue and causes sensorineural hearing loss in mice.

Parker A, Hardisty-Hughes RE, Wisby L, Joyce S, Brown SD. Parker A, et al. Mamm Genome. 2010 Dec;21(11-12):565-76. doi: 10.1007/s00335-010-9306-2. Epub 2010 Nov 30. Mamm Genome. 2010. PMID: 21116635 Free PMC article.

7

HIF-VEGF pathways are critical for chronic otitis media in Junbo and Jeff mouse mutants.

Cheeseman MT, Tyrer HE, Williams D, Hough TA, Pathak P, Romero MR, Hilton H, Bali S, Parker A, Vizor L, Purnell T, Vowell K, Wells S, Bhutta MF, Potter PK, Brown SD. Cheeseman MT, et al. Among authors: parker a. PLoS Genet. 2011 Oct;7(10):e1002336. doi: 10.1371/journal.pgen.1002336. Epub 2011 Oct 20. PLoS Genet. 2011. PMID: 22028672 Free PMC article.

8

Otitis media in the Tgif knockout mouse implicates TGFβ signalling in chronic middle ear inflammatory disease.

Tateossian H, Morse S, Parker A, Mburu P, Warr N, Acevedo-Arozena A, Cheeseman M, Wells S, Brown SD. Tateossian H, et al. Among authors: parker a. Hum Mol Genet. 2013 Jul 1;22(13):2553-65. doi: 10.1093/hmg/ddt103. Epub 2013 Mar 3. Hum Mol Genet. 2013. PMID: 23459932 Free PMC article.

9

The actin-binding proteins eps8 and gelsolin have complementary roles in regulating the growth and stability of mechanosensory hair bundles of mammalian cochlear outer hair cells.

Olt J, Mburu P, Johnson SL, Parker A, Kuhn S, Bowl M, Marcotti W, Brown SD. Olt J, et al. Among authors: parker a. PLoS One. 2014 Jan 27;9(1):e87331. doi: 10.1371/journal.pone.0087331. eCollection 2014. PLoS One. 2014. PMID: 24475274 Free PMC article.

10

The goya mouse mutant reveals distinct newly identified roles for MAP3K1 in the development and survival of cochlear sensory hair cells.

Parker A, Cross SH, Jackson IJ, Hardisty-Hughes R, Morse S, Nicholson G, Coghill E, Bowl MR, Brown SD. Parker A, et al. Dis Model Mech. 2015 Dec;8(12):1555-68. doi: 10.1242/dmm.023176. Epub 2015 Nov 5. Dis Model Mech. 2015. PMID: 26542706 Free PMC article.

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