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Bench-to-bedside translation of chimeric antigen receptor (CAR) T cells using a multiscale systems pharmacokinetic-pharmacodynamic model: A case study with anti-BCMA CAR-T.
Singh AP, Chen W, Zheng X, Mody H, Carpenter TJ, Zong A, Heald DL. Singh AP, et al. Among authors: zheng x. CPT Pharmacometrics Syst Pharmacol. 2021 Apr;10(4):362-376. doi: 10.1002/psp4.12598. Epub 2021 Mar 24. CPT Pharmacometrics Syst Pharmacol. 2021. PMID: 33565700 Free PMC article. Clinical Trial.
Industry Perspective on First-in-Human and Clinical Pharmacology Strategies to Support Clinical Development of T-Cell Engaging Bispecific Antibodies for Cancer Therapy.
Nagaraja Shastri P, Shah N, Lechmann M, Mody H, Retter MW, Zhu M, Li T, Wang J, Shaik N, Zheng X, Ovacik M, Hua F, Jawa V, Boetsch C, Cao Y, Burke J, Datta K, Gadkar K, Upreti V, Betts A. Nagaraja Shastri P, et al. Among authors: zheng x. Clin Pharmacol Ther. 2024 Sep 19. doi: 10.1002/cpt.3439. Online ahead of print. Clin Pharmacol Ther. 2024. PMID: 39295563 Review.
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