Brohawn PZ - Search Results

1

Trial of Anifrolumab in Active Systemic Lupus Erythematosus.

Morand EF, Furie R, Tanaka Y, Bruce IN, Askanase AD, Richez C, Bae SC, Brohawn PZ, Pineda L, Berglind A, Tummala R; TULIP-2 Trial Investigators. Morand EF, et al. Among authors: brohawn pz. N Engl J Med. 2020 Jan 16;382(3):211-221. doi: 10.1056/NEJMoa1912196. Epub 2019 Dec 18. N Engl J Med. 2020. PMID: 31851795 Clinical Trial.

2

Long-Term Safety and Efficacy of Anifrolumab in Adults With Systemic Lupus Erythematosus: Results of a Phase II Open-Label Extension Study.

Chatham WW, Furie R, Saxena A, Brohawn P, Schwetje E, Abreu G, Tummala R. Chatham WW, et al. Arthritis Rheumatol. 2021 May;73(5):816-825. doi: 10.1002/art.41598. Epub 2021 Mar 24. Arthritis Rheumatol. 2021. PMID: 33225631 Free PMC article. Clinical Trial.

3

The Pathogenesis, Molecular Mechanisms, and Therapeutic Potential of the Interferon Pathway in Systemic Lupus Erythematosus and Other Autoimmune Diseases.

Ramaswamy M, Tummala R, Streicher K, Nogueira da Costa A, Brohawn PZ. Ramaswamy M, et al. Among authors: brohawn pz. Int J Mol Sci. 2021 Oct 19;22(20):11286. doi: 10.3390/ijms222011286. Int J Mol Sci. 2021. PMID: 34681945 Free PMC article. Review.

4

Anifrolumab, an Anti-Interferon-α Receptor Monoclonal Antibody, in Moderate-to-Severe Systemic Lupus Erythematosus.

Furie R, Khamashta M, Merrill JT, Werth VP, Kalunian K, Brohawn P, Illei GG, Drappa J, Wang L, Yoo S; CD1013 Study Investigators. Furie R, et al. Arthritis Rheumatol. 2017 Feb;69(2):376-386. doi: 10.1002/art.39962. Arthritis Rheumatol. 2017. PMID: 28130918 Free PMC article. Clinical Trial.

5

Type I interferon gene signature test-low and -high patients with systemic lupus erythematosus have distinct gene expression signatures.

Brohawn PZ, Streicher K, Higgs BW, Morehouse C, Liu H, Illei G, Ranade K. Brohawn PZ, et al. Lupus. 2019 Nov;28(13):1524-1533. doi: 10.1177/0961203319885447. Epub 2019 Oct 29. Lupus. 2019. PMID: 31660791 Clinical Trial.

6

Targeting the interferon pathway with sifalimumab for the treatment of systemic lupus erythematosus.

Greth W, Robbie GJ, Brohawn P, Hultquist M, Yao B. Greth W, et al. Immunotherapy. 2017 Jan;9(1):57-70. doi: 10.2217/imt-2016-0090. Immunotherapy. 2017. PMID: 28000522 Review.

7

Baseline Plasma Cell Gene Signature Predicts Improvement in Systemic Sclerosis Skin Scores Following Treatment With Inebilizumab (MEDI-551) and Correlates With Disease Activity in Systemic Lupus Erythematosus and Chronic Obstructive Pulmonary Disease.

Streicher K, Sridhar S, Kuziora M, Morehouse CA, Higgs BW, Sebastian Y, Groves CJ, Pilataxi F, Brohawn PZ, Herbst R, Ranade K. Streicher K, et al. Among authors: brohawn pz. Arthritis Rheumatol. 2018 Dec;70(12):2087-2095. doi: 10.1002/art.40656. Epub 2018 Oct 22. Arthritis Rheumatol. 2018. PMID: 29956883 Clinical Trial.

8

Neutralization of interferon-alpha/beta-inducible genes and downstream effect in a phase I trial of an anti-interferon-alpha monoclonal antibody in systemic lupus erythematosus.

Yao Y, Richman L, Higgs BW, Morehouse CA, de los Reyes M, Brohawn P, Zhang J, White B, Coyle AJ, Kiener PA, Jallal B. Yao Y, et al. Arthritis Rheum. 2009 Jun;60(6):1785-96. doi: 10.1002/art.24557. Arthritis Rheum. 2009. PMID: 19479852 Free article. Clinical Trial.

9

Patients with systemic lupus erythematosus, myositis, rheumatoid arthritis and scleroderma share activation of a common type I interferon pathway.

Higgs BW, Liu Z, White B, Zhu W, White WI, Morehouse C, Brohawn P, Kiener PA, Richman L, Fiorentino D, Greenberg SA, Jallal B, Yao Y. Higgs BW, et al. Ann Rheum Dis. 2011 Nov;70(11):2029-36. doi: 10.1136/ard.2011.150326. Epub 2011 Jul 28. Ann Rheum Dis. 2011. PMID: 21803750 Clinical Trial.

10

Development of Potential Pharmacodynamic and Diagnostic Markers for Anti-IFN-α Monoclonal Antibody Trials in Systemic Lupus Erythematosus.

Yao Y, Higgs BW, Morehouse C, de Los Reyes M, Trigona W, Brohawn P, White W, Zhang J, White B, Coyle AJ, Kiener PA, Jallal B. Yao Y, et al. Hum Genomics Proteomics. 2009 Nov 17;2009:374312. doi: 10.4061/2009/374312. Hum Genomics Proteomics. 2009. PMID: 20948567 Free PMC article.

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