Cristini A - Search Results

1

N⁶-methyladenosine regulates the stability of RNA:DNA hybrids in human cells.

Abakir A, Giles TC, Cristini A, Foster JM, Dai N, Starczak M, Rubio-Roldan A, Li M, Eleftheriou M, Crutchley J, Flatt L, Young L, Gaffney DJ, Denning C, Dalhus B, Emes RD, Gackowski D, Corrêa IR Jr, Garcia-Perez JL, Klungland A, Gromak N, Ruzov A. Abakir A, et al. Among authors: cristini a. Nat Genet. 2020 Jan;52(1):48-55. doi: 10.1038/s41588-019-0549-x. Epub 2019 Dec 16. Nat Genet. 2020. PMID: 31844323 Free PMC article.

2

Senataxin: Genome Guardian at the Interface of Transcription and Neurodegeneration.

Groh M, Albulescu LO, Cristini A, Gromak N. Groh M, et al. Among authors: cristini a. J Mol Biol. 2017 Oct 27;429(21):3181-3195. doi: 10.1016/j.jmb.2016.10.021. Epub 2016 Oct 19. J Mol Biol. 2017. PMID: 27771483 Review.

3

RNA/DNA Hybrid Interactome Identifies DXH9 as a Molecular Player in Transcriptional Termination and R-Loop-Associated DNA Damage.

Cristini A, Groh M, Kristiansen MS, Gromak N. Cristini A, et al. Cell Rep. 2018 May 8;23(6):1891-1905. doi: 10.1016/j.celrep.2018.04.025. Cell Rep. 2018. PMID: 29742442 Free PMC article.

4

Dual Processing of R-Loops and Topoisomerase I Induces Transcription-Dependent DNA Double-Strand Breaks.

Cristini A, Ricci G, Britton S, Salimbeni S, Huang SN, Marinello J, Calsou P, Pommier Y, Favre G, Capranico G, Gromak N, Sordet O. Cristini A, et al. Cell Rep. 2019 Sep 17;28(12):3167-3181.e6. doi: 10.1016/j.celrep.2019.08.041. Cell Rep. 2019. PMID: 31533039 Free PMC article.

5

Transcription-dependent DNA double-strand breaks and human disease.

Cristini A, Gromak N, Sordet O. Cristini A, et al. Mol Cell Oncol. 2020 Jan 10;7(2):1691905. doi: 10.1080/23723556.2019.1691905. eCollection 2020. Mol Cell Oncol. 2020. PMID: 32158914 Free PMC article.

6

RNase H2, mutated in Aicardi-Goutières syndrome, resolves co-transcriptional R-loops to prevent DNA breaks and inflammation.

Cristini A, Tellier M, Constantinescu F, Accalai C, Albulescu LO, Heiringhoff R, Bery N, Sordet O, Murphy S, Gromak N. Cristini A, et al. Nat Commun. 2022 May 26;13(1):2961. doi: 10.1038/s41467-022-30604-0. Nat Commun. 2022. PMID: 35618715 Free PMC article.

7

APOBEC3B regulates R-loops and promotes transcription-associated mutagenesis in cancer.

McCann JL, Cristini A, Law EK, Lee SY, Tellier M, Carpenter MA, Beghè C, Kim JJ, Sanchez A, Jarvis MC, Stefanovska B, Temiz NA, Bergstrom EN, Salamango DJ, Brown MR, Murphy S, Alexandrov LB, Miller KM, Gromak N, Harris RS. McCann JL, et al. Among authors: cristini a. Nat Genet. 2023 Oct;55(10):1721-1734. doi: 10.1038/s41588-023-01504-w. Epub 2023 Sep 21. Nat Genet. 2023. PMID: 37735199 Free PMC article.

8

RhoB promotes cancer initiation by protecting keratinocytes from UVB-induced apoptosis but limits tumor aggressiveness.

Meyer N, Peyret-Lacombe A, Canguilhem B, Médale-Giamarchi C, Mamouni K, Cristini A, Monferran S, Lamant L, Filleron T, Pradines A, Sordet O, Favre G. Meyer N, et al. Among authors: cristini a. J Invest Dermatol. 2014 Jan;134(1):203-212. doi: 10.1038/jid.2013.278. Epub 2013 Jun 21. J Invest Dermatol. 2014. PMID: 23792460 Free article.

9

RhoB promotes γH2AX dephosphorylation and DNA double-strand break repair.

Mamouni K, Cristini A, Guirouilh-Barbat J, Monferran S, Lemarié A, Faye JC, Lopez BS, Favre G, Sordet O. Mamouni K, et al. Among authors: cristini a. Mol Cell Biol. 2014 Aug;34(16):3144-55. doi: 10.1128/MCB.01525-13. Epub 2014 Jun 9. Mol Cell Biol. 2014. PMID: 24912678 Free PMC article.

10

DNA-PK triggers histone ubiquitination and signaling in response to DNA double-strand breaks produced during the repair of transcription-blocking topoisomerase I lesions.

Cristini A, Park JH, Capranico G, Legube G, Favre G, Sordet O. Cristini A, et al. Nucleic Acids Res. 2016 Feb 18;44(3):1161-78. doi: 10.1093/nar/gkv1196. Epub 2015 Nov 17. Nucleic Acids Res. 2016. PMID: 26578593 Free PMC article.

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