The IDH2 R172K mutation associated with angioimmunoblastic T-cell lymphoma produces 2HG in T cells and impacts lymphoid development.
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Lemonnier F, et al. Among authors: pujals a.
Proc Natl Acad Sci U S A. 2016 Dec 27;113(52):15084-15089. doi: 10.1073/pnas.1617929114. Epub 2016 Dec 12.
Proc Natl Acad Sci U S A. 2016.
PMID: 27956631
Free PMC article.