Lighthouse JK - Search Results

1

A Novel Role of Cyclic Nucleotide Phosphodiesterase 10A in Pathological Cardiac Remodeling and Dysfunction.

Chen S, Zhang Y, Lighthouse JK, Mickelsen DM, Wu J, Yao P, Small EM, Yan C. Chen S, et al. Among authors: lighthouse jk. Circulation. 2020 Jan 21;141(3):217-233. doi: 10.1161/CIRCULATIONAHA.119.042178. Epub 2019 Dec 5. Circulation. 2020. PMID: 31801360 Free PMC article.

2

Transcriptional control of cardiac fibroblast plasticity.

Lighthouse JK, Small EM. Lighthouse JK, et al. J Mol Cell Cardiol. 2016 Feb;91:52-60. doi: 10.1016/j.yjmcc.2015.12.016. Epub 2015 Dec 22. J Mol Cell Cardiol. 2016. PMID: 26721596 Free PMC article. Review.

3

Small proline-rich protein 2B drives stress-dependent p53 degradation and fibroblast proliferation in heart failure.

Burke RM, Lighthouse JK, Quijada P, Dirkx RA Jr, Rosenberg A, Moravec CS, Alexis JD, Small EM. Burke RM, et al. Among authors: lighthouse jk. Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):E3436-E3445. doi: 10.1073/pnas.1717423115. Epub 2018 Mar 26. Proc Natl Acad Sci U S A. 2018. PMID: 29581288 Free PMC article.

4

Exercise promotes a cardioprotective gene program in resident cardiac fibroblasts.

Lighthouse JK, Burke RM, Velasquez LS, Dirkx RA Jr, Aiezza A 2nd, Moravec CS, Alexis JD, Rosenberg A, Small EM. Lighthouse JK, et al. JCI Insight. 2019 Jan 10;4(1):e92098. doi: 10.1172/jci.insight.92098. JCI Insight. 2019. PMID: 30626739 Free PMC article.

5

Pre-existing fibroblasts of epicardial origin are the primary source of pathological fibrosis in cardiac ischemia and aging.

Quijada P, Misra A, Velasquez LS, Burke RM, Lighthouse JK, Mickelsen DM, Dirkx RA Jr, Small EM. Quijada P, et al. Among authors: lighthouse jk. J Mol Cell Cardiol. 2019 Apr;129:92-104. doi: 10.1016/j.yjmcc.2019.01.015. Epub 2019 Feb 13. J Mol Cell Cardiol. 2019. PMID: 30771308 Free PMC article.

6

Sacubitril/Valsartan Decreases Cardiac Fibrosis in Left Ventricle Pressure Overload by Restoring PKG Signaling in Cardiac Fibroblasts.

Burke RM, Lighthouse JK, Mickelsen DM, Small EM. Burke RM, et al. Among authors: lighthouse jk. Circ Heart Fail. 2019 Apr;12(4):e005565. doi: 10.1161/CIRCHEARTFAILURE.118.005565. Circ Heart Fail. 2019. PMID: 30998392 Free PMC article.

7

Protective transcriptional mechanisms in cardiomyocytes and cardiac fibroblasts.

Brand CS, Lighthouse JK, Trembley MA. Brand CS, et al. Among authors: lighthouse jk. J Mol Cell Cardiol. 2019 Jul;132:1-12. doi: 10.1016/j.yjmcc.2019.04.023. Epub 2019 Apr 28. J Mol Cell Cardiol. 2019. PMID: 31042488 Free PMC article. Review.

8

Prevention of Fibrosis and Pathological Cardiac Remodeling by Salinomycin.

Burke RM, Dirkx RA Jr, Quijada P, Lighthouse JK, Mohan A, O'Brien M, Wojciechowski W, Woeller CF, Phipps RP, Alexis JD, Ashton JM, Small EM. Burke RM, et al. Among authors: lighthouse jk. Circ Res. 2021 May 28;128(11):1663-1678. doi: 10.1161/CIRCRESAHA.120.317791. Epub 2021 Apr 7. Circ Res. 2021. PMID: 33825488 Free PMC article.

9

Cell-Based Phenotypic Screen for Antifibrotic Compounds Targets Eicosanoid Metabolism.

Lighthouse JK, Small EM. Lighthouse JK, et al. Circ Res. 2023 Jan 6;132(1):30-33. doi: 10.1161/CIRCRESAHA.122.322272. Epub 2023 Jan 5. Circ Res. 2023. PMID: 36603069 Free PMC article. No abstract available.

10

p53 Regulates the Extent of Fibroblast Proliferation and Fibrosis in Left Ventricle Pressure Overload.

Liu X, Burke RM, Lighthouse JK, Baker CD, Dirkx RA Jr, Kang B, Chakraborty Y, Mickelsen DM, Twardowski JJ, Mello SS, Ashton JM, Small EM. Liu X, et al. Among authors: lighthouse jk. Circ Res. 2023 Jul 21;133(3):271-287. doi: 10.1161/CIRCRESAHA.121.320324. Epub 2023 Jul 6. Circ Res. 2023. PMID: 37409456 Free PMC article.

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