Papageorge AG - Search Results

1

Gain-of-Function RHOA Mutations Promote Focal Adhesion Kinase Activation and Dependency in Diffuse Gastric Cancer.

Zhang H, Schaefer A, Wang Y, Hodge RG, Blake DR, Diehl JN, Papageorge AG, Stachler MD, Liao J, Zhou J, Wu Z, Akarca FG, de Klerk LK, Derks S, Pierobon M, Hoadley KA, Wang TC, Church G, Wong KK, Petricoin EF, Cox AD, Lowy DR, Der CJ, Bass AJ. Zhang H, et al. Among authors: papageorge ag. Cancer Discov. 2020 Feb;10(2):288-305. doi: 10.1158/2159-8290.CD-19-0811. Epub 2019 Nov 26. Cancer Discov. 2020. PMID: 31771969 Free PMC article.

2

Full activity of the deleted in liver cancer 1 (DLC1) tumor suppressor depends on an LD-like motif that binds talin and focal adhesion kinase (FAK).

Li G, Du X, Vass WC, Papageorge AG, Lowy DR, Qian X. Li G, et al. Among authors: papageorge ag. Proc Natl Acad Sci U S A. 2011 Oct 11;108(41):17129-34. doi: 10.1073/pnas.1112122108. Epub 2011 Oct 3. Proc Natl Acad Sci U S A. 2011. PMID: 21969587 Free PMC article.

3

Receptor tyrosine kinase activation of RhoA is mediated by AKT phosphorylation of DLC1.

Tripathi BK, Grant T, Qian X, Zhou M, Mertins P, Wang D, Papageorge AG, Tarasov SG, Hunter KW, Carr SA, Lowy DR. Tripathi BK, et al. Among authors: papageorge ag. J Cell Biol. 2017 Dec 4;216(12):4255-4270. doi: 10.1083/jcb.201703105. Epub 2017 Nov 7. J Cell Biol. 2017. PMID: 29114068 Free PMC article.

4

Functional interaction of tumor suppressor DLC1 and caveolin-1 in cancer cells.

Du X, Qian X, Papageorge A, Schetter AJ, Vass WC, Liu X, Braverman R, Robles AI, Lowy DR. Du X, et al. Cancer Res. 2012 Sep 1;72(17):4405-16. doi: 10.1158/0008-5472.CAN-12-0777. Epub 2012 Jun 12. Cancer Res. 2012. PMID: 22693251 Free PMC article.

5

CDK5 is a major regulator of the tumor suppressor DLC1.

Tripathi BK, Qian X, Mertins P, Wang D, Papageorge AG, Carr SA, Lowy DR. Tripathi BK, et al. Among authors: papageorge ag. J Cell Biol. 2014 Dec 8;207(5):627-42. doi: 10.1083/jcb.201405105. Epub 2014 Dec 1. J Cell Biol. 2014. PMID: 25452387 Free PMC article.

6

Mechanistic aspects of signaling through Ras in NIH 3T3 cells.

Zhang K, Papageorge AG, Lowy DR. Zhang K, et al. Among authors: papageorge ag. Science. 1992 Jul 31;257(5070):671-4. doi: 10.1126/science.1496380. Science. 1992. PMID: 1496380

7

The Tensin-3 protein, including its SH2 domain, is phosphorylated by Src and contributes to tumorigenesis and metastasis.

Qian X, Li G, Vass WC, Papageorge A, Walker RC, Asnaghi L, Steinbach PJ, Tosato G, Hunter K, Lowy DR. Qian X, et al. Cancer Cell. 2009 Sep 8;16(3):246-58. doi: 10.1016/j.ccr.2009.07.031. Cancer Cell. 2009. PMID: 19732724 Free PMC article.

8

SRC and ERK cooperatively phosphorylate DLC1 and attenuate its Rho-GAP and tumor suppressor functions.

Tripathi BK, Anderman MF, Qian X, Zhou M, Wang D, Papageorge AG, Lowy DR. Tripathi BK, et al. Among authors: papageorge ag. J Cell Biol. 2019 Sep 2;218(9):3060-3076. doi: 10.1083/jcb.201810098. Epub 2019 Jul 15. J Cell Biol. 2019. PMID: 31308216 Free PMC article.

9

E-cadherin negatively regulates neoplastic growth in non-small cell lung cancer: role of Rho GTPases.

Asnaghi L, Vass WC, Quadri R, Day PM, Qian X, Braverman R, Papageorge AG, Lowy DR. Asnaghi L, et al. Among authors: papageorge ag. Oncogene. 2010 May 13;29(19):2760-71. doi: 10.1038/onc.2010.39. Epub 2010 Mar 15. Oncogene. 2010. PMID: 20228844 Free PMC article.

10

Inhibition of cell growth by lovastatin is independent of ras function.

DeClue JE, Vass WC, Papageorge AG, Lowy DR, Willumsen BM. DeClue JE, et al. Among authors: papageorge ag. Cancer Res. 1991 Jan 15;51(2):712-7. Cancer Res. 1991. PMID: 1985788

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