Jaeschke H - Search Results

1

The Effect of 4-Methylpyrazole on Oxidative Metabolism of Acetaminophen in Human Volunteers.

Kang AM, Padilla-Jones A, Fisher ES, Akakpo JY, Jaeschke H, Rumack BH, Gerkin RD, Curry SC. Kang AM, et al. Among authors: jaeschke h. J Med Toxicol. 2020 Apr;16(2):169-176. doi: 10.1007/s13181-019-00740-z. Epub 2019 Nov 25. J Med Toxicol. 2020. PMID: 31768936 Free PMC article. Clinical Trial.

2

c-Jun N-terminal kinase modulates oxidant stress and peroxynitrite formation independent of inducible nitric oxide synthase in acetaminophen hepatotoxicity.

Saito C, Lemasters JJ, Jaeschke H. Saito C, et al. Among authors: jaeschke h. Toxicol Appl Pharmacol. 2010 Jul;246(1-2):8-17. doi: 10.1016/j.taap.2010.04.015. Epub 2010 Apr 25. Toxicol Appl Pharmacol. 2010. PMID: 20423716 Free PMC article.

3

The oxygen tension modulates acetaminophen-induced mitochondrial oxidant stress and cell injury in cultured hepatocytes.

Yan HM, Ramachandran A, Bajt ML, Lemasters JJ, Jaeschke H. Yan HM, et al. Among authors: jaeschke h. Toxicol Sci. 2010 Oct;117(2):515-23. doi: 10.1093/toxsci/kfq208. Epub 2010 Jul 8. Toxicol Sci. 2010. PMID: 20616211 Free PMC article.

4

The impact of partial manganese superoxide dismutase (SOD2)-deficiency on mitochondrial oxidant stress, DNA fragmentation and liver injury during acetaminophen hepatotoxicity.

Ramachandran A, Lebofsky M, Weinman SA, Jaeschke H. Ramachandran A, et al. Among authors: jaeschke h. Toxicol Appl Pharmacol. 2011 Mar 15;251(3):226-33. doi: 10.1016/j.taap.2011.01.004. Epub 2011 Jan 15. Toxicol Appl Pharmacol. 2011. PMID: 21241727 Free PMC article.

5

Apoptosis-inducing factor modulates mitochondrial oxidant stress in acetaminophen hepatotoxicity.

Bajt ML, Ramachandran A, Yan HM, Lebofsky M, Farhood A, Lemasters JJ, Jaeschke H. Bajt ML, et al. Among authors: jaeschke h. Toxicol Sci. 2011 Aug;122(2):598-605. doi: 10.1093/toxsci/kfr116. Epub 2011 May 13. Toxicol Sci. 2011. PMID: 21572097 Free PMC article.

6

Activation of autophagy protects against acetaminophen-induced hepatotoxicity.

Ni HM, Bockus A, Boggess N, Jaeschke H, Ding WX. Ni HM, et al. Among authors: jaeschke h. Hepatology. 2012 Jan;55(1):222-32. doi: 10.1002/hep.24690. Epub 2011 Dec 6. Hepatology. 2012. PMID: 21932416 Free PMC article.

7

The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation.

McGill MR, Sharpe MR, Williams CD, Taha M, Curry SC, Jaeschke H. McGill MR, et al. Among authors: jaeschke h. J Clin Invest. 2012 Apr;122(4):1574-83. doi: 10.1172/JCI59755. Epub 2012 Mar 1. J Clin Invest. 2012. PMID: 22378043 Free PMC article.

8

Liver-specific loss of Atg5 causes persistent activation of Nrf2 and protects against acetaminophen-induced liver injury.

Ni HM, Boggess N, McGill MR, Lebofsky M, Borude P, Apte U, Jaeschke H, Ding WX. Ni HM, et al. Among authors: jaeschke h. Toxicol Sci. 2012 Jun;127(2):438-50. doi: 10.1093/toxsci/kfs133. Epub 2012 Apr 5. Toxicol Sci. 2012. PMID: 22491424 Free PMC article.

9

Acetaminophen-induced liver injury in rats and mice: comparison of protein adducts, mitochondrial dysfunction, and oxidative stress in the mechanism of toxicity.

McGill MR, Williams CD, Xie Y, Ramachandran A, Jaeschke H. McGill MR, et al. Among authors: jaeschke h. Toxicol Appl Pharmacol. 2012 Nov 1;264(3):387-94. doi: 10.1016/j.taap.2012.08.015. Epub 2012 Aug 23. Toxicol Appl Pharmacol. 2012. PMID: 22980195 Free PMC article.

10

Purinergic receptor antagonist A438079 protects against acetaminophen-induced liver injury by inhibiting p450 isoenzymes, not by inflammasome activation.

Xie Y, Williams CD, McGill MR, Lebofsky M, Ramachandran A, Jaeschke H. Xie Y, et al. Among authors: jaeschke h. Toxicol Sci. 2013 Jan;131(1):325-35. doi: 10.1093/toxsci/kfs283. Epub 2012 Sep 17. Toxicol Sci. 2013. PMID: 22986947 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

473 results

Search Page

Filters