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Autism spectrum disorder and attention deficit hyperactivity disorder have a similar burden of rare protein-truncating variants.
Satterstrom FK, Walters RK, Singh T, Wigdor EM, Lescai F, Demontis D, Kosmicki JA, Grove J, Stevens C, Bybjerg-Grauholm J, Bækvad-Hansen M, Palmer DS, Maller JB; iPSYCH-Broad Consortium; Nordentoft M, Mors O, Robinson EB, Hougaard DM, Werge TM, Bo Mortensen P, Neale BM, Børglum AD, Daly MJ. Satterstrom FK, et al. Among authors: borglum ad. Nat Neurosci. 2019 Dec;22(12):1961-1965. doi: 10.1038/s41593-019-0527-8. Epub 2019 Nov 25. Nat Neurosci. 2019. PMID: 31768057 Free PMC article.
Common variants conferring risk of schizophrenia.
Stefansson H, Ophoff RA, Steinberg S, Andreassen OA, Cichon S, Rujescu D, Werge T, Pietiläinen OP, Mors O, Mortensen PB, Sigurdsson E, Gustafsson O, Nyegaard M, Tuulio-Henriksson A, Ingason A, Hansen T, Suvisaari J, Lonnqvist J, Paunio T, Børglum AD, Hartmann A, Fink-Jensen A, Nordentoft M, Hougaard D, Norgaard-Pedersen B, Böttcher Y, Olesen J, Breuer R, Möller HJ, Giegling I, Rasmussen HB, Timm S, Mattheisen M, Bitter I, Réthelyi JM, Magnusdottir BB, Sigmundsson T, Olason P, Masson G, Gulcher JR, Haraldsson M, Fossdal R, Thorgeirsson TE, Thorsteinsdottir U, Ruggeri M, Tosato S, Franke B, Strengman E, Kiemeney LA; Genetic Risk and Outcome in Psychosis (GROUP); Melle I, Djurovic S, Abramova L, Kaleda V, Sanjuan J, de Frutos R, Bramon E, Vassos E, Fraser G, Ettinger U, Picchioni M, Walker N, Toulopoulou T, Need AC, Ge D, Yoon JL, Shianna KV, Freimer NB, Cantor RM, Murray R, Kong A, Golimbet V, Carracedo A, Arango C, Costas J, Jönsson EG, Terenius L, Agartz I, Petursson H, Nöthen MM, Rietschel M, Matthews PM, Muglia P, Peltonen L, St Clair D, Goldstein DB, Stefansson K, Collier DA. Stefansson H, et al. Among authors: borglum ad. Nature. 2009 Aug 6;460(7256):744-7. doi: 10.1038/nature08186. Epub 2009 Jul 1. Nature. 2009. PMID: 19571808 Free PMC article.
Genome-wide scans using archived neonatal dried blood spot samples.
Hollegaard MV, Grauholm J, Børglum A, Nyegaard M, Nørgaard-Pedersen B, Ørntoft T, Mortensen PB, Wiuf C, Mors O, Didriksen M, Thorsen P, Hougaard DM. Hollegaard MV, et al. BMC Genomics. 2009 Jul 4;10:297. doi: 10.1186/1471-2164-10-297. BMC Genomics. 2009. PMID: 19575812 Free PMC article.
Support of association between BRD1 and both schizophrenia and bipolar affective disorder.
Nyegaard M, Severinsen JE, Als TD, Hedemand A, Straarup S, Nordentoft M, McQuillin A, Bass N, Lawrence J, Thirumalai S, Pereira ACP, Kandaswamy R, Lydall GJ, Sklar P, Scolnick E, Purcell S, Curtis D, Gurling HMD, Mortensen PB, Mors O, Børglum AD. Nyegaard M, et al. Among authors: borglum ad. Am J Med Genet B Neuropsychiatr Genet. 2010 Mar 5;153B(2):582-591. doi: 10.1002/ajmg.b.31023. Am J Med Genet B Neuropsychiatr Genet. 2010. PMID: 19693800
Support for a bipolar affective disorder susceptibility locus on chromosome 12q24.3.
Buttenschøn HN, Foldager L, Flint TJ, Olsen IM, Deleuran T, Nyegaard M, Hansen MM, Kallunki P, Christensen KV, Blackwood DH, Muir WJ, Straarup SE, Als TD, Nordentoft M, Børglum AD, Mors O. Buttenschøn HN, et al. Among authors: borglum ad. Psychiatr Genet. 2010 Jun;20(3):93-101. doi: 10.1097/YPG.0b013e32833a2066. Psychiatr Genet. 2010. PMID: 20410851
366 results