Taguchi A - Search Results

1

Synthesis and structure-activity relationship studies of IgG-binding peptides focused on the C-terminal histidine residue.

Muguruma K, Ito M, Fukuda A, Kishimoto S, Taguchi A, Takayama K, Taniguchi A, Ito Y, Hayashi Y. Muguruma K, et al. Among authors: taguchi a. Medchemcomm. 2019 Aug 1;10(10):1789-1795. doi: 10.1039/c9md00294d. eCollection 2019 Oct 1. Medchemcomm. 2019. PMID: 31762965 Free PMC article.

2

Design, synthesis, and biological evaluation of novel dipeptide-type SARS-CoV 3CL protease inhibitors: structure-activity relationship study.

Thanigaimalai P, Konno S, Yamamoto T, Koiwai Y, Taguchi A, Takayama K, Yakushiji F, Akaji K, Kiso Y, Kawasaki Y, Chen SE, Naser-Tavakolian A, Schön A, Freire E, Hayashi Y. Thanigaimalai P, et al. Among authors: taguchi a. Eur J Med Chem. 2013 Jul;65:436-47. doi: 10.1016/j.ejmech.2013.05.005. Epub 2013 May 20. Eur J Med Chem. 2013. PMID: 23747811 Free PMC article.

3

Development of potent dipeptide-type SARS-CoV 3CL protease inhibitors with novel P3 scaffolds: design, synthesis, biological evaluation, and docking studies.

Thanigaimalai P, Konno S, Yamamoto T, Koiwai Y, Taguchi A, Takayama K, Yakushiji F, Akaji K, Chen SE, Naser-Tavakolian A, Schön A, Freire E, Hayashi Y. Thanigaimalai P, et al. Among authors: taguchi a. Eur J Med Chem. 2013 Oct;68:372-84. doi: 10.1016/j.ejmech.2013.07.037. Epub 2013 Aug 9. Eur J Med Chem. 2013. PMID: 23994330 Free PMC article.

4

Negamycin analogue with readthrough-promoting activity as a potential drug candidate for duchenne muscular dystrophy.

Taguchi A, Nishiguchi S, Shiozuka M, Nomoto T, Ina M, Nojima S, Matsuda R, Nonomura Y, Kiso Y, Yamazaki Y, Yakushiji F, Hayashi Y. Taguchi A, et al. ACS Med Chem Lett. 2012 Jan 2;3(2):118-22. doi: 10.1021/ml200245t. eCollection 2012 Feb 9. ACS Med Chem Lett. 2012. PMID: 24900441 Free PMC article.

5

Discovery of selective hexapeptide agonists to human neuromedin U receptors types 1 and 2.

Takayama K, Mori K, Taketa K, Taguchi A, Yakushiji F, Minamino N, Miyazato M, Kangawa K, Hayashi Y. Takayama K, et al. Among authors: taguchi a. J Med Chem. 2014 Aug 14;57(15):6583-93. doi: 10.1021/jm500599s. Epub 2014 Jul 18. J Med Chem. 2014. PMID: 24999562

6

Discovery of natural products possessing selective eukaryotic readthrough activity: 3-epi-deoxynegamycin and its leucine adduct.

Taguchi A, Hamada K, Kotake M, Shiozuka M, Nakaminami H, Pillaiyar T, Takayama K, Yakushiji F, Noguchi N, Usui T, Matsuda R, Hayashi Y. Taguchi A, et al. ChemMedChem. 2014 Oct;9(10):2233-7. doi: 10.1002/cmdc.201402208. Epub 2014 Jul 9. ChemMedChem. 2014. PMID: 25044534

7

Development of a new benzophenone-diketopiperazine-type potent antimicrotubule agent possessing a 2-pyridine structure.

Hayashi Y, Takeno H, Chinen T, Muguruma K, Okuyama K, Taguchi A, Takayama K, Yakushiji F, Miura M, Usui T, Hayashi Y. Hayashi Y, et al. Among authors: taguchi a. ACS Med Chem Lett. 2014 Jul 23;5(10):1094-8. doi: 10.1021/ml5001883. eCollection 2014 Oct 9. ACS Med Chem Lett. 2014. PMID: 25313318 Free PMC article.

8

3-Nitro-2-pyridinesulfenyl-mediated solid-phase disulfide ligation in the synthesis of disulfide bond-containing cyclic peptides.

Taguchi A, Fukumoto K, Asahina Y, Kajiyama A, Shimura S, Hamada K, Takayama K, Yakushiji F, Hojo H, Hayashi Y. Taguchi A, et al. Org Biomol Chem. 2015 Mar 21;13(11):3186-9. doi: 10.1039/c5ob00030k. Org Biomol Chem. 2015. PMID: 25657109

9

Discovery of potent hexapeptide agonists to human neuromedin u receptor 1 and identification of their serum metabolites.

Takayama K, Mori K, Sohma Y, Taketa K, Taguchi A, Yakushiji F, Minamino N, Miyazato M, Kangawa K, Hayashi Y. Takayama K, et al. Among authors: taguchi a. ACS Med Chem Lett. 2015 Jan 28;6(3):302-7. doi: 10.1021/ml500494j. eCollection 2015 Mar 12. ACS Med Chem Lett. 2015. PMID: 25815150 Free PMC article.

10

Structure-Activity Relationship Studies of 3-epi-Deoxynegamycin Derivatives as Potent Readthrough Drug Candidates.

Hamada K, Taguchi A, Kotake M, Aita S, Murakami S, Takayama K, Yakushiji F, Hayashi Y. Hamada K, et al. Among authors: taguchi a. ACS Med Chem Lett. 2015 May 11;6(6):689-94. doi: 10.1021/acsmedchemlett.5b00121. eCollection 2015 Jun 11. ACS Med Chem Lett. 2015. PMID: 26101575 Free PMC article.

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