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Page 1
Impact of Minor Structural Modifications on Properties of a Series of mTOR Inhibitors.
Ouvry G, Clary L, Tomas L, Aurelly M, Bonnary L, Borde E, Bouix-Peter C, Chantalat L, Defoin-Platel C, Deret S, Forissier M, Harris CS, Isabet T, Lamy L, Luzy AP, Pascau J, Soulet C, Taddei A, Taquet N, Thoreau E, Varvier E, Vial E, Hennequin LF. Ouvry G, et al. Among authors: chantalat l. ACS Med Chem Lett. 2019 Oct 4;10(11):1561-1567. doi: 10.1021/acsmedchemlett.9b00401. eCollection 2019 Nov 14. ACS Med Chem Lett. 2019. PMID: 31749911 Free PMC article.
Discovery of phenoxyindazoles and phenylthioindazoles as RORγ inverse agonists.
Ouvry G, Bouix-Peter C, Ciesielski F, Chantalat L, Christin O, Comino C, Duvert D, Feret C, Harris CS, Lamy L, Luzy AP, Musicki B, Orfila D, Pascau J, Parnet V, Perrin A, Pierre R, Polge G, Raffin C, Rival Y, Taquet N, Thoreau E, Hennequin LF. Ouvry G, et al. Among authors: chantalat l. Bioorg Med Chem Lett. 2016 Dec 1;26(23):5802-5808. doi: 10.1016/j.bmcl.2016.10.023. Epub 2016 Oct 12. Bioorg Med Chem Lett. 2016. PMID: 27815118
New Caspase-1 inhibitor by scaffold hopping into bio-inspired 3D-fragment space.
Brethon A, Chantalat L, Christin O, Clary L, Fournier JF, Gastreich M, Harris CS, Isabet T, Pascau J, Thoreau E, Roche D, Rodeschini V. Brethon A, et al. Among authors: chantalat l. Bioorg Med Chem Lett. 2017 Dec 15;27(24):5373-5377. doi: 10.1016/j.bmcl.2017.11.015. Epub 2017 Nov 9. Bioorg Med Chem Lett. 2017. PMID: 29157864
Rational Drug Design of Topically Administered Caspase 1 Inhibitors for the Treatment of Inflammatory Acne.
Fournier JF, Clary L, Chambon S, Dumais L, Harris CS, Millois C, Pierre R, Talano S, Thoreau É, Aubert J, Aurelly M, Bouix-Peter C, Brethon A, Chantalat L, Christin O, Comino C, El-Bazbouz G, Ghilini AL, Isabet T, Lardy C, Luzy AP, Mathieu C, Mebrouk K, Orfila D, Pascau J, Reverse K, Roche D, Rodeschini V, Hennequin LF. Fournier JF, et al. Among authors: chantalat l. J Med Chem. 2018 May 10;61(9):4030-4051. doi: 10.1021/acs.jmedchem.8b00067. Epub 2018 Apr 24. J Med Chem. 2018. PMID: 29648825
Structure-based design of Trifarotene (CD5789), a potent and selective RARγ agonist for the treatment of acne.
Thoreau E, Arlabosse JM, Bouix-Peter C, Chambon S, Chantalat L, Daver S, Dumais L, Duvert G, Feret A, Ouvry G, Pascau J, Raffin C, Rodeville N, Soulet C, Tabet S, Talano S, Portal T. Thoreau E, et al. Among authors: chantalat l. Bioorg Med Chem Lett. 2018 Jun 1;28(10):1736-1741. doi: 10.1016/j.bmcl.2018.04.036. Epub 2018 Apr 15. Bioorg Med Chem Lett. 2018. PMID: 29706423
Squaramides as novel class I and IIB histone deacetylase inhibitors for topical treatment of cutaneous t-cell lymphoma.
Fournier JF, Bhurruth-Alcor Y, Musicki B, Aubert J, Aurelly M, Bouix-Peter C, Bouquet K, Chantalat L, Delorme M, Drean B, Duvert G, Fleury-Bregeot N, Gauthier B, Grisendi K, Harris CS, Hennequin LF, Isabet T, Joly F, Lafitte G, Millois C, Morgentin R, Pascau J, Piwnica D, Rival Y, Soulet C, Thoreau É, Tomas L. Fournier JF, et al. Among authors: chantalat l. Bioorg Med Chem Lett. 2018 Sep 15;28(17):2985-2992. doi: 10.1016/j.bmcl.2018.06.029. Epub 2018 Jun 18. Bioorg Med Chem Lett. 2018. PMID: 30122227
[A skin hypopigmentation].
Nabitz C, Chantalat L, Fourgeaud C, Vignes S. Nabitz C, et al. Among authors: chantalat l. Rev Med Interne. 2021 Jul;42(7):513-514. doi: 10.1016/j.revmed.2020.11.004. Epub 2020 Dec 3. Rev Med Interne. 2021. PMID: 33280839 French. No abstract available.
[Puffy hand syndrome: A little-known diagnosis].
Chantalat L, Simon M, Fourgeaud C, Vignes S. Chantalat L, et al. Rev Med Interne. 2020 Oct;41(10):700-703. doi: 10.1016/j.revmed.2020.05.020. Epub 2020 Jul 14. Rev Med Interne. 2020. PMID: 32674894 French.
Des vésicules cutanées.
Martiano M, Chantalat L, Simon M, Fourgeaud C, Vignes S. Martiano M, et al. Among authors: chantalat l. Rev Med Interne. 2020 Sep;41(9):637-638. doi: 10.1016/j.revmed.2020.03.007. Epub 2020 Apr 28. Rev Med Interne. 2020. PMID: 32359817 French. No abstract available.
33 results