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Trp53 haploinsufficiency modifies EGFR-driven peripheral nerve sheath tumorigenesis.
Rahrmann EP, Moriarity BS, Otto GM, Watson AL, Choi K, Collins MH, Wallace M, Webber BR, Forster CL, Rizzardi AE, Schmechel SC, Ratner N, Largaespada DA. Rahrmann EP, et al. Among authors: moriarity bs. Am J Pathol. 2014 Jul;184(7):2082-98. doi: 10.1016/j.ajpath.2014.04.006. Epub 2014 May 13. Am J Pathol. 2014. PMID: 24832557 Free PMC article.
PVT1 dependence in cancer with MYC copy-number increase.
Tseng YY, Moriarity BS, Gong W, Akiyama R, Tiwari A, Kawakami H, Ronning P, Reuland B, Guenther K, Beadnell TC, Essig J, Otto GM, O'Sullivan MG, Largaespada DA, Schwertfeger KL, Marahrens Y, Kawakami Y, Bagchi A. Tseng YY, et al. Among authors: moriarity bs. Nature. 2014 Aug 7;512(7512):82-6. doi: 10.1038/nature13311. Epub 2014 Jun 22. Nature. 2014. PMID: 25043044 Free PMC article.
Ras oncogene-independent activation of RALB signaling is a targetable mechanism of escape from NRAS(V12) oncogene addiction in acute myeloid leukemia.
Pomeroy EJ, Lee LA, Lee RDW, Schirm DK, Temiz NA, Ma J, Gruber TA, Diaz-Flores E, Moriarity BS, Downing JR, Shannon KM, Largaespada DA, Eckfeldt CE. Pomeroy EJ, et al. Among authors: moriarity bs. Oncogene. 2017 Jun 8;36(23):3263-3273. doi: 10.1038/onc.2016.471. Epub 2016 Dec 19. Oncogene. 2017. PMID: 27991934 Free PMC article.
Rapid generation of Col7a1-/- mouse model of recessive dystrophic epidermolysis bullosa and partial rescue via immunosuppressive dermal mesenchymal stem cells.
Webber BR, O'Connor KT, McElmurry RT, Durgin EN, Eide CR, Lees CJ, Riddle MJ, Mathews WE, Frank NY, Kluth MA, Ganss C, Moriarity BS, Frank MH, Osborn MJ, Tolar J. Webber BR, et al. Among authors: moriarity bs. Lab Invest. 2017 Oct;97(10):1218-1224. doi: 10.1038/labinvest.2017.85. Epub 2017 Sep 11. Lab Invest. 2017. PMID: 28892093 Free PMC article.
CRISPR/Cas9 library screening for drug target discovery.
Kurata M, Yamamoto K, Moriarity BS, Kitagawa M, Largaespada DA. Kurata M, et al. Among authors: moriarity bs. J Hum Genet. 2018 Feb;63(2):179-186. doi: 10.1038/s10038-017-0376-9. Epub 2017 Nov 20. J Hum Genet. 2018. PMID: 29158600 Review.
Highly multiplexed genome engineering using CRISPR/Cas9 gRNA arrays.
Kurata M, Wolf NK, Lahr WS, Weg MT, Kluesner MG, Lee S, Hui K, Shiraiwa M, Webber BR, Moriarity BS. Kurata M, et al. Among authors: moriarity bs. PLoS One. 2018 Sep 17;13(9):e0198714. doi: 10.1371/journal.pone.0198714. eCollection 2018. PLoS One. 2018. PMID: 30222773 Free PMC article.
88 results