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Discovery and in Vivo Evaluation of Macrocyclic Mcl-1 Inhibitors Featuring an α-Hydroxy Phenylacetic Acid Pharmacophore or Bioisostere.
Rescourio G, Gonzalez AZ, Jabri S, Belmontes B, Moody G, Whittington D, Huang X, Caenepeel S, Cardozo M, Cheng AC, Chow D, Dou H, Jones A, Kelly RC, Li Y, Lizarzaburu M, Lo MC, Mallari R, Meleza C, Rew Y, Simonovich S, Sun D, Turcotte S, Yan X, Wong SG, Yanez E, Zancanella M, Houze J, Medina JC, Hughes PE, Brown SP. Rescourio G, et al. Among authors: turcotte s. J Med Chem. 2019 Nov 27;62(22):10258-10271. doi: 10.1021/acs.jmedchem.9b01310. Epub 2019 Nov 18. J Med Chem. 2019. PMID: 31736296
Optimization of triazoles as novel and potent nonphlorizin SGLT2 inhibitors.
Du X, Lizarzaburu M, Turcotte S, Lee T, Greenberg J, Shan B, Fan P, Ling Y, Medina JC, Houze J. Du X, et al. Among authors: turcotte s. Bioorg Med Chem Lett. 2011 Jun 15;21(12):3774-9. doi: 10.1016/j.bmcl.2011.04.053. Epub 2011 Apr 20. Bioorg Med Chem Lett. 2011. PMID: 21565497
Phenylalanine derivatives as GPR142 agonists for the treatment of type II diabetes.
Du X, Kim YJ, Lai S, Chen X, Lizarzaburu M, Turcotte S, Fu Z, Liu Q, Zhang Y, Motani A, Oda K, Okuyama R, Nara F, Murakoshi M, Fu A, Reagan JD, Fan P, Xiong Y, Shen W, Li L, Houze J, Medina JC. Du X, et al. Among authors: turcotte s. Bioorg Med Chem Lett. 2012 Oct 1;22(19):6218-23. doi: 10.1016/j.bmcl.2012.08.015. Epub 2012 Aug 10. Bioorg Med Chem Lett. 2012. PMID: 22926069
Rational Design of Macrocyclic Noncovalent Inhibitors of SARS-CoV-2 Mpro from a DNA-Encoded Chemical Library Screening Hit That Demonstrate Potent Inhibition against Pan-Coronavirus Homologues and Nirmatrelvir-Resistant Variants.
Wang X, Gotchev D, Fan KY, Vega MM, Mani N, McGovern-Gooch K, Cuconati A, Tercero B, Wang X, Carpino P, Maskos K, Centrella PA, Schmitt A, Preuss F, Prasad A, Chen CY, Clark MA, Guilinger JP, Johnstone S, von König K, Keefe AD, Liu J, Turcotte S, Zhang Y, Konz Makino DL, Lam AM, Cole AG, Sofia MJ. Wang X, et al. Among authors: turcotte s. J Med Chem. 2024 Nov 14;67(21):19623-19667. doi: 10.1021/acs.jmedchem.4c02009. Epub 2024 Oct 25. J Med Chem. 2024. PMID: 39453309
Caregivers' burden of care during emergency department care transitions among older adults: a mixed methods cohort study.
Germain N, Jémus-Gonzalez E, Couture V, Côté É, Morin M, Toulouse-Fournier A, Bert L, Giguère R, Sinha S, Sourial N, Chartier LB, Witteman HO, Légaré F, Samb R, Turcotte S, Chandavong S, Abrougui L, Robitaille J, Archambault PM; Network of Canadian Emergency Researchers. Germain N, et al. Among authors: turcotte s. BMC Geriatr. 2024 Sep 28;24(1):788. doi: 10.1186/s12877-024-05388-1. BMC Geriatr. 2024. PMID: 39342196 Free PMC article.
Radiomics analysis of baseline computed tomography to predict oncological outcomes in patients treated for resectable colorectal cancer liver metastasis.
Montagnon E, Cerny M, Hamilton V, Derennes T, Ilinca A, Elforaici MEA, Jabbour G, Rafie E, Wu A, Perdigon Romero F, Cadrin-Chênevert A, Kadoury S, Turcotte S, Tang A. Montagnon E, et al. Among authors: turcotte s. PLoS One. 2024 Sep 11;19(9):e0307815. doi: 10.1371/journal.pone.0307815. eCollection 2024. PLoS One. 2024. PMID: 39259736 Free PMC article.
231 results