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Immunological ignorance is an enabling feature of the oligo-clonal T cell response to melanoma neoantigens.
Linette GP, Becker-Hapak M, Skidmore ZL, Baroja ML, Xu C, Hundal J, Spencer DH, Fu W, Cummins C, Robnett M, Kaabinejadian S, Hildebrand WH, Magrini V, Demeter R, Krupnick AS, Griffith OL, Griffith M, Mardis ER, Carreno BM. Linette GP, et al. Among authors: baroja ml. Proc Natl Acad Sci U S A. 2019 Nov 19;116(47):23662-23670. doi: 10.1073/pnas.1906026116. Epub 2019 Nov 4. Proc Natl Acad Sci U S A. 2019. PMID: 31685621 Free PMC article.
Biochemical and functional characterization of mutant KRAS epitopes validates this oncoprotein for immunological targeting.
Bear AS, Blanchard T, Cesare J, Ford MJ, Richman LP, Xu C, Baroja ML, McCuaig S, Costeas C, Gabunia K, Scholler J, Posey AD Jr, O'Hara MH, Smole A, Powell DJ Jr, Garcia BA, Vonderheide RH, Linette GP, Carreno BM. Bear AS, et al. Among authors: baroja ml. Nat Commun. 2021 Jul 16;12(1):4365. doi: 10.1038/s41467-021-24562-2. Nat Commun. 2021. PMID: 34272369 Free PMC article.
Preclinical evaluation of cancer immune therapy using patient-derived tumor antigen-specific T cells in a novel xenograft platform.
Shenoy GN, Greene CJ, Bhatta M, Baroja ML, Loyall JL, Balu-Iyer SV, Kelleher RJ Jr, Carreno BM, Linette GP, Shultz LD, Bankert RB. Shenoy GN, et al. Among authors: baroja ml. Clin Transl Immunology. 2021 Feb 2;10(2):e1246. doi: 10.1002/cti2.1246. eCollection 2021. Clin Transl Immunology. 2021. PMID: 33552509 Free PMC article.
44 results