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A MultiTEP platform-based epitope vaccine targeting the phosphatase activating domain (PAD) of tau: therapeutic efficacy in PS19 mice.
Hovakimyan A, Antonyan T, Shabestari SK, Svystun O, Chailyan G, Coburn MA, Carlen-Jones W, Petrushina I, Chadarevian JP, Zagorski K, Petrovsky N, Cribbs DH, Agadjanyan MG, Ghochikyan A, Davtyan H. Hovakimyan A, et al. Among authors: agadjanyan mg. Sci Rep. 2019 Oct 29;9(1):15455. doi: 10.1038/s41598-019-51809-2. Sci Rep. 2019. PMID: 31664089 Free PMC article.
Immunization with a vaccine that combines the expression of MUC1 and B7 co-stimulatory molecules prolongs the survival of mice and delays the appearance of mouse mammary tumors.
Vasilevko V, Ghochikyan A, Sadzikava N, Petrushina I, Tran M, Cohen EP, Kesslak PJ, Cribbs DH, Nicolson GL, Agadjanyan MG. Vasilevko V, et al. Among authors: agadjanyan mg. Clin Exp Metastasis. 2003;20(6):489-98. doi: 10.1023/a:1025802610724. Clin Exp Metastasis. 2003. PMID: 14598882
Mimotopes of conformational epitopes in fibrillar beta-amyloid.
Gevorkian G, Petrushina I, Manoutcharian K, Ghochikyan A, Acero G, Vasilevko V, Cribbs DH, Agadjanyan MG. Gevorkian G, et al. Among authors: agadjanyan mg. J Neuroimmunol. 2004 Nov;156(1-2):10-20. doi: 10.1016/j.jneuroim.2004.06.004. J Neuroimmunol. 2004. PMID: 15465592
Immunization with fibrillar Abeta(1-42) in young and aged canines: Antibody generation and characteristics, and effects on CSF and brain Abeta.
Head E, Barrett EG, Murphy MP, Das P, Nistor M, Sarsoza F, Glabe CC, Kayed R, Milton S, Vasilevko V, Milgram NW, Agadjanyan MG, Cribbs DH, Cotman CW. Head E, et al. Among authors: agadjanyan mg. Vaccine. 2006 Apr 5;24(15):2824-34. doi: 10.1016/j.vaccine.2005.12.058. Epub 2006 Jan 19. Vaccine. 2006. PMID: 16460841
86 results