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iRhom2 inhibits bile duct obstruction-induced liver fibrosis.
Sundaram B, Behnke K, Belancic A, Al-Salihi MA, Thabet Y, Polz R, Pellegrino R, Zhuang Y, Shinde PV, Xu HC, Vasilevska J, Longerich T, Herebian D, Mayatepek E, Bock HH, May P, Kordes C, Aghaeepour N, Mak TW, Keitel V, Häussinger D, Scheller J, Pandyra AA, Lang KS, Lang PA. Sundaram B, et al. Among authors: scheller j. Sci Signal. 2019 Oct 29;12(605):eaax1194. doi: 10.1126/scisignal.aax1194. Sci Signal. 2019. PMID: 31662486
Cellular senescence or EGFR signaling induces Interleukin 6 (IL-6) receptor expression controlled by mammalian target of rapamycin (mTOR).
Garbers C, Kuck F, Aparicio-Siegmund S, Konzak K, Kessenbrock M, Sommerfeld A, Häussinger D, Lang PA, Brenner D, Mak TW, Rose-John S, Essmann F, Schulze-Osthoff K, Piekorz RP, Scheller J. Garbers C, et al. Among authors: scheller j. Cell Cycle. 2013 Nov 1;12(21):3421-32. doi: 10.4161/cc.26431. Epub 2013 Sep 18. Cell Cycle. 2013. PMID: 24047696 Free PMC article.
Recombinant p35 from bacteria can form Interleukin (IL-)12, but Not IL-35.
Aparicio-Siegmund S, Moll JM, Lokau J, Grusdat M, Schröder J, Plöhn S, Rose-John S, Grötzinger J, Lang PA, Scheller J, Garbers C. Aparicio-Siegmund S, et al. Among authors: scheller j. PLoS One. 2014 Sep 26;9(9):e107990. doi: 10.1371/journal.pone.0107990. eCollection 2014. PLoS One. 2014. PMID: 25259790 Free PMC article.
Deletions in the cytoplasmic domain of iRhom1 and iRhom2 promote shedding of the TNF receptor by the protease ADAM17.
Maney SK, McIlwain DR, Polz R, Pandyra AA, Sundaram B, Wolff D, Ohishi K, Maretzky T, Brooke MA, Evers A, Vasudevan AA, Aghaeepour N, Scheller J, Münk C, Häussinger D, Mak TW, Nolan GP, Kelsell DP, Blobel CP, Lang KS, Lang PA. Maney SK, et al. Among authors: scheller j. Sci Signal. 2015 Nov 3;8(401):ra109. doi: 10.1126/scisignal.aac5356. Sci Signal. 2015. PMID: 26535007 Free PMC article.
B Cell-Mediated Maintenance of Cluster of Differentiation 169-Positive Cells Is Critical for Liver Regeneration.
Behnke K, Zhuang Y, Xu HC, Sundaram B, Reich M, Shinde PV, Huang J, Modares NF, Tumanov AV, Polz R, Scheller J, Ware CF, Pfeffer K, Keitel V, Häussinger D, Pandyra AA, Lang KS, Lang PA. Behnke K, et al. Among authors: scheller j. Hepatology. 2018 Dec;68(6):2348-2361. doi: 10.1002/hep.30088. Epub 2018 Nov 5. Hepatology. 2018. PMID: 29742809 Free PMC article.
Synthetic cytokine receptors transmit biological signals using artificial ligands.
Engelowski E, Schneider A, Franke M, Xu H, Clemen R, Lang A, Baran P, Binsch C, Knebel B, Al-Hasani H, Moll JM, Floß DM, Lang PA, Scheller J. Engelowski E, et al. Among authors: scheller j. Nat Commun. 2018 May 23;9(1):2034. doi: 10.1038/s41467-018-04454-8. Nat Commun. 2018. PMID: 29789554 Free PMC article.
IL-23R Signaling Plays No Role in Myocardial Infarction.
Engelowski E, Modares NF, Gorressen S, Bouvain P, Semmler D, Alter C, Ding Z, Flögel U, Schrader J, Xu H, Lang PA, Fischer J, Floss DM, Scheller J. Engelowski E, et al. Among authors: scheller j. Sci Rep. 2018 Nov 20;8(1):17078. doi: 10.1038/s41598-018-35188-8. Sci Rep. 2018. PMID: 30459442 Free PMC article.
241 results