Ghosh D - Search Results

1

Phosphorylation of human placental aromatase CYP19A1.

Ghosh D, Egbuta C, Kanyo JE, Lam TT. Ghosh D, et al. Biochem J. 2019 Nov 15;476(21):3313-3331. doi: 10.1042/BCJ20190633. Biochem J. 2019. PMID: 31652308 Free PMC article.

2

Higher order organization of human placental aromatase.

Ghosh D, Jiang W, Lo J, Egbuta C. Ghosh D, et al. Steroids. 2011 Jul;76(8):753-8. doi: 10.1016/j.steroids.2011.02.030. Epub 2011 Mar 8. Steroids. 2011. PMID: 21392520 Free PMC article.

3

Motion and flexibility in human cytochrome p450 aromatase.

Jiang W, Ghosh D. Jiang W, et al. Among authors: ghosh d. PLoS One. 2012;7(2):e32565. doi: 10.1371/journal.pone.0032565. Epub 2012 Feb 27. PLoS One. 2012. PMID: 22384274 Free PMC article.

4

Novel aromatase inhibitors by structure-guided design.

Ghosh D, Lo J, Morton D, Valette D, Xi J, Griswold J, Hubbell S, Egbuta C, Jiang W, An J, Davies HM. Ghosh D, et al. J Med Chem. 2012 Oct 11;55(19):8464-76. doi: 10.1021/jm300930n. Epub 2012 Sep 24. J Med Chem. 2012. PMID: 22951074 Free PMC article.

5

Structural basis for the functional roles of critical residues in human cytochrome p450 aromatase.

Lo J, Di Nardo G, Griswold J, Egbuta C, Jiang W, Gilardi G, Ghosh D. Lo J, et al. Among authors: ghosh d. Biochemistry. 2013 Aug 27;52(34):5821-9. doi: 10.1021/bi400669h. Epub 2013 Aug 16. Biochemistry. 2013. PMID: 23899247 Free PMC article.

6

Mechanism of inhibition of estrogen biosynthesis by azole fungicides.

Egbuta C, Lo J, Ghosh D. Egbuta C, et al. Among authors: ghosh d. Endocrinology. 2014 Dec;155(12):4622-8. doi: 10.1210/en.2014-1561. Epub 2014 Sep 22. Endocrinology. 2014. PMID: 25243857 Free PMC article.

7

Evidence for an elevated aspartate pK(a) in the active site of human aromatase.

Di Nardo G, Breitner M, Bandino A, Ghosh D, Jennings GK, Hackett JC, Gilardi G. Di Nardo G, et al. Among authors: ghosh d. J Biol Chem. 2015 Jan 9;290(2):1186-96. doi: 10.1074/jbc.M114.595108. Epub 2014 Nov 25. J Biol Chem. 2015. PMID: 25425647 Free PMC article.

8

Recent Progress in the Discovery of Next Generation Inhibitors of Aromatase from the Structure-Function Perspective.

Ghosh D, Lo J, Egbuta C. Ghosh D, et al. J Med Chem. 2016 Jun 9;59(11):5131-48. doi: 10.1021/acs.jmedchem.5b01281. Epub 2016 Jan 19. J Med Chem. 2016. PMID: 26689671 Free PMC article. Review.

9

Testosterone complex and non-steroidal ligands of human aromatase.

Ghosh D, Egbuta C, Lo J. Ghosh D, et al. J Steroid Biochem Mol Biol. 2018 Jul;181:11-19. doi: 10.1016/j.jsbmb.2018.02.009. Epub 2018 Feb 21. J Steroid Biochem Mol Biol. 2018. PMID: 29476820 Free PMC article.

10

X-ray structure of human aromatase reveals an androgen-specific active site.

Ghosh D, Griswold J, Erman M, Pangborn W. Ghosh D, et al. J Steroid Biochem Mol Biol. 2010 Feb 28;118(4-5):197-202. doi: 10.1016/j.jsbmb.2009.09.012. Epub 2009 Oct 4. J Steroid Biochem Mol Biol. 2010. PMID: 19808095 Free PMC article.

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