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Organoid single-cell genomic atlas uncovers human-specific features of brain development.
Kanton S, Boyle MJ, He Z, Santel M, Weigert A, Sanchís-Calleja F, Guijarro P, Sidow L, Fleck JS, Han D, Qian Z, Heide M, Huttner WB, Khaitovich P, Pääbo S, Treutlein B, Camp JG. Kanton S, et al. Among authors: fleck js. Nature. 2019 Oct;574(7778):418-422. doi: 10.1038/s41586-019-1654-9. Epub 2019 Oct 16. Nature. 2019. PMID: 31619793
Inferring and perturbing cell fate regulomes in human brain organoids.
Fleck JS, Jansen SMJ, Wollny D, Zenk F, Seimiya M, Jain A, Okamoto R, Santel M, He Z, Camp JG, Treutlein B. Fleck JS, et al. Nature. 2023 Sep;621(7978):365-372. doi: 10.1038/s41586-022-05279-8. Epub 2022 Oct 5. Nature. 2023. PMID: 36198796 Free PMC article.
Multimodal spatiotemporal phenotyping of human retinal organoid development.
Wahle P, Brancati G, Harmel C, He Z, Gut G, Del Castillo JS, Xavier da Silveira Dos Santos A, Yu Q, Noser P, Fleck JS, Gjeta B, Pavlinić D, Picelli S, Hess M, Schmidt GW, Lummen TTA, Hou Y, Galliker P, Goldblum D, Balogh M, Cowan CS, Scholl HPN, Roska B, Renner M, Pelkmans L, Treutlein B, Camp JG. Wahle P, et al. Among authors: fleck js. Nat Biotechnol. 2023 Dec;41(12):1765-1775. doi: 10.1038/s41587-023-01747-2. Epub 2023 May 8. Nat Biotechnol. 2023. PMID: 37156914 Free PMC article.
What is a cell type?
Fleck JS, Camp JG, Treutlein B. Fleck JS, et al. Science. 2023 Aug 18;381(6659):733-734. doi: 10.1126/science.adf6162. Epub 2023 Aug 17. Science. 2023. PMID: 37590360
Single-cell brain organoid screening identifies developmental defects in autism.
Li C, Fleck JS, Martins-Costa C, Burkard TR, Themann J, Stuempflen M, Peer AM, Vertesy Á, Littleboy JB, Esk C, Elling U, Kasprian G, Corsini NS, Treutlein B, Knoblich JA. Li C, et al. Among authors: fleck js. Nature. 2023 Sep;621(7978):373-380. doi: 10.1038/s41586-023-06473-y. Epub 2023 Sep 13. Nature. 2023. PMID: 37704762 Free PMC article.
13 results