Wulff H - Search Results

1

The Trials and Tribulations of Structure Assisted Design of K_Ca Channel Activators.

Shim H, Brown BM, Singh L, Singh V, Fettinger JC, Yarov-Yarovoy V, Wulff H. Shim H, et al. Among authors: wulff h. Front Pharmacol. 2019 Sep 20;10:972. doi: 10.3389/fphar.2019.00972. eCollection 2019. Front Pharmacol. 2019. PMID: 31616290 Free PMC article.

2

Triarylmethanes, a new class of cx50 inhibitors.

Bodendiek SB, Rubinos C, Trelles MP, Coleman N, Jenkins DP, Wulff H, Srinivas M. Bodendiek SB, et al. Among authors: wulff h. Front Pharmacol. 2012 Jun 6;3:106. doi: 10.3389/fphar.2012.00106. eCollection 2012. Front Pharmacol. 2012. PMID: 22685432 Free PMC article.

3

Endothelial small-conductance and intermediate-conductance KCa channels: an update on their pharmacology and usefulness as cardiovascular targets.

Wulff H, Köhler R. Wulff H, et al. J Cardiovasc Pharmacol. 2013 Feb;61(2):102-12. doi: 10.1097/FJC.0b013e318279ba20. J Cardiovasc Pharmacol. 2013. PMID: 23107876 Free PMC article. Review.

4

Channels: Sticking to nooks and crannies.

Wulff H, Yarov-Yarovoy V. Wulff H, et al. Nat Chem Biol. 2013 Aug;9(8):473-4. doi: 10.1038/nchembio.1292. Nat Chem Biol. 2013. PMID: 23868316

5

Development of a QPatch automated electrophysiology assay for identifying KCa3.1 inhibitors and activators.

Jenkins DP, Yu W, Brown BM, Løjkner LD, Wulff H. Jenkins DP, et al. Among authors: wulff h. Assay Drug Dev Technol. 2013 Nov-Dec;11(9-10):551-60. doi: 10.1089/adt.2013.543. Assay Drug Dev Technol. 2013. PMID: 24351043 Free PMC article.

6

Alterations in cerebellar physiology are associated with a stiff-legged gait in Atcay(ji-hes) mice.

Luna-Cancalon K, Sikora KM, Pappas SS, Singh V, Wulff H, Paulson HL, Burmeister M, Shakkottai VG. Luna-Cancalon K, et al. Among authors: wulff h. Neurobiol Dis. 2014 Jul;67:140-8. doi: 10.1016/j.nbd.2014.03.020. Epub 2014 Apr 12. Neurobiol Dis. 2014. PMID: 24727095 Free PMC article.

7

New positive Ca2+-activated K+ channel gating modulators with selectivity for KCa3.1.

Coleman N, Brown BM, Oliván-Viguera A, Singh V, Olmstead MM, Valero MS, Köhler R, Wulff H. Coleman N, et al. Among authors: wulff h. Mol Pharmacol. 2014 Sep;86(3):342-57. doi: 10.1124/mol.114.093286. Epub 2014 Jun 23. Mol Pharmacol. 2014. PMID: 24958817 Free PMC article.

8

Dyclonine rescues frataxin deficiency in animal models and buccal cells of patients with Friedreich's ataxia.

Sahdeo S, Scott BD, McMackin MZ, Jasoliya M, Brown B, Wulff H, Perlman SL, Pook MA, Cortopassi GA. Sahdeo S, et al. Among authors: wulff h. Hum Mol Genet. 2014 Dec 20;23(25):6848-62. doi: 10.1093/hmg/ddu408. Epub 2014 Aug 11. Hum Mol Genet. 2014. PMID: 25113747 Free PMC article.

9

The riluzole derivative 2-amino-6-trifluoromethylthio-benzothiazole (SKA-19), a mixed KCa2 activator and NaV blocker, is a potent novel anticonvulsant.

Coleman N, Nguyen HM, Cao Z, Brown BM, Jenkins DP, Zolkowska D, Chen YJ, Tanaka BS, Goldin AL, Rogawski MA, Pessah IN, Wulff H. Coleman N, et al. Among authors: wulff h. Neurotherapeutics. 2015 Jan;12(1):234-49. doi: 10.1007/s13311-014-0305-y. Neurotherapeutics. 2015. PMID: 25256961 Free PMC article.

10

A novel pan-negative-gating modulator of KCa2/3 channels, fluoro-di-benzoate, RA-2, inhibits endothelium-derived hyperpolarization-type relaxation in coronary artery and produces bradycardia in vivo.

Oliván-Viguera A, Valero MS, Coleman N, Brown BM, Laría C, Murillo MD, Gálvez JA, Díaz-de-Villegas MD, Wulff H, Badorrey R, Köhler R. Oliván-Viguera A, et al. Among authors: wulff h. Mol Pharmacol. 2015 Feb;87(2):338-48. doi: 10.1124/mol.114.095745. Epub 2014 Dec 2. Mol Pharmacol. 2015. PMID: 25468883 Free PMC article.

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