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Slow phosphorylation of a tyrosine residue in LAT optimizes T cell ligand discrimination.
Nat Immunol. 2019 Nov;20(11):1481-1493. doi: 10.1038/s41590-019-0502-2. Epub 2019 Oct 14.
Nat Immunol. 2019.
PMID: 31611699
Free PMC article.
An electrostatic selection mechanism controls sequential kinase signaling downstream of the T cell receptor.
Shah NH, Wang Q, Yan Q, Karandur D, Kadlecek TA, Fallahee IR, Russ WP, Ranganathan R, Weiss A, Kuriyan J.
Shah NH, et al. Among authors: fallahee ir.
Elife. 2016 Oct 4;5:e20105. doi: 10.7554/eLife.20105.
Elife. 2016.
PMID: 27700984
Free PMC article.
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A Two-Step Process of Effector Programming Governs CD4+ T Cell Fate Determination Induced by Antigenic Activation in the Steady State.
Opejin A, Surnov A, Misulovin Z, Pherson M, Gross C, Iberg CA, Fallahee I, Bourque J, Dorsett D, Hawiger D.
Opejin A, et al.
Cell Rep. 2020 Nov 24;33(8):108424. doi: 10.1016/j.celrep.2020.108424.
Cell Rep. 2020.
PMID: 33238127
Free PMC article.
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TNF-α sculpts a maturation process in vivo by pruning tolerogenic dendritic cells.
Iberg CA, Bourque J, Fallahee I, Son S, Hawiger D.
Iberg CA, et al.
Cell Rep. 2022 Apr 12;39(2):110657. doi: 10.1016/j.celrep.2022.110657.
Cell Rep. 2022.
PMID: 35417681
Free PMC article.
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