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Pitx2 modulates a Tbx5-dependent gene regulatory network to maintain atrial rhythm.
Nadadur RD, Broman MT, Boukens B, Mazurek SR, Yang X, van den Boogaard M, Bekeny J, Gadek M, Ward T, Zhang M, Qiao Y, Martin JF, Seidman CE, Seidman J, Christoffels V, Efimov IR, McNally EM, Weber CR, Moskowitz IP. Nadadur RD, et al. Among authors: gadek m. Sci Transl Med. 2016 Aug 31;8(354):354ra115. doi: 10.1126/scitranslmed.aaf4891. Sci Transl Med. 2016. PMID: 27582060 Free PMC article.
Transcription-factor-dependent enhancer transcription defines a gene regulatory network for cardiac rhythm.
Yang XH, Nadadur RD, Hilvering CR, Bianchi V, Werner M, Mazurek SR, Gadek M, Shen KM, Goldman JA, Tyan L, Bekeny J, Hall JM, Lee N, Perez-Cervantes C, Burnicka-Turek O, Poss KD, Weber CR, de Laat W, Ruthenburg AJ, Moskowitz IP. Yang XH, et al. Among authors: gadek m. Elife. 2017 Dec 27;6:e31683. doi: 10.7554/eLife.31683. Elife. 2017. PMID: 29280435 Free PMC article.
A calcium transport mechanism for atrial fibrillation in Tbx5-mutant mice.
Dai W, Laforest B, Tyan L, Shen KM, Nadadur RD, Alvarado FJ, Mazurek SR, Lazarevic S, Gadek M, Wang Y, Li Y, Valdivia HH, Shen L, Broman MT, Moskowitz IP, Weber CR. Dai W, et al. Among authors: gadek m. Elife. 2019 Mar 21;8:e41814. doi: 10.7554/eLife.41814. Elife. 2019. PMID: 30896405 Free PMC article.
ZO-1 Regulates Intercalated Disc Composition and Atrioventricular Node Conduction.
Dai W, Nadadur RD, Brennan JA, Smith HL, Shen KM, Gadek M, Laforest B, Wang M, Gemel J, Li Y, Zhang J, Ziman BD, Yan J, Ai X, Beyer EC, Lakata EG, Kasthuri N, Efimov IR, Broman MT, Moskowitz IP, Shen L, Weber CR. Dai W, et al. Among authors: gadek m. Circ Res. 2020 Jul 3;127(2):e28-e43. doi: 10.1161/CIRCRESAHA.119.316415. Epub 2020 Apr 29. Circ Res. 2020. PMID: 32347164 Free PMC article.
A Genomic Link From Heart Failure to Atrial Fibrillation Risk: FOG2 Modulates a TBX5/GATA4-Dependent Atrial Gene Regulatory Network.
Broman MT, Nadadur RD, Perez-Cervantes C, Burnicka-Turek O, Lazarevic S, Gams A, Laforest B, Steimle JD, Iddir S, Wang Z, Smith L, Mazurek SR, Olivey HE, Zhou P, Gadek M, Shen KM, Khan Z, Theisen JWM, Yang XH, Ikegami K, Efimov IR, Pu WT, Weber CR, McNally EM, Svensson EC, Moskowitz IP. Broman MT, et al. Among authors: gadek m. Circulation. 2024 Apr 9;149(15):1205-1230. doi: 10.1161/CIRCULATIONAHA.123.066804. Epub 2024 Jan 8. Circulation. 2024. PMID: 38189150
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