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210 results

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Page 1
Human signal transducer and activator of transcription 5b (STAT5b) mutation causes dysregulated human natural killer cell maturation and impaired lytic function.
Vargas-Hernández A, Witalisz-Siepracka A, Prchal-Murphy M, Klein K, Mahapatra S, Al-Herz W, Mace EM, Carisey AF, Orange JS, Sexl V, Forbes LR. Vargas-Hernández A, et al. Among authors: sexl v. J Allergy Clin Immunol. 2020 Jan;145(1):345-357.e9. doi: 10.1016/j.jaci.2019.09.016. Epub 2019 Oct 7. J Allergy Clin Immunol. 2020. PMID: 31600547 Free PMC article.
PI3Kδ is essential for tumor clearance mediated by cytotoxic T lymphocytes.
Putz EM, Prchal-Murphy M, Simma OA, Forster F, Koenig X, Stockinger H, Piekorz RP, Freissmuth M, Müller M, Sexl V, Zebedin-Brandl E. Putz EM, et al. Among authors: sexl v. PLoS One. 2012;7(7):e40852. doi: 10.1371/journal.pone.0040852. Epub 2012 Jul 13. PLoS One. 2012. PMID: 22808277 Free PMC article.
Targeting PI3Kδ: One man's meat is another man's poison.
Prchal-Murphy M, Putz EM, Freissmuth M, Sexl V, Zebedin-Brandl E. Prchal-Murphy M, et al. Among authors: sexl v. Oncoimmunology. 2013 Jan 1;2(1):e22272. doi: 10.4161/onci.22272. Oncoimmunology. 2013. PMID: 23482629 Free PMC article.
NK cell development in bone marrow and liver: site matters.
Gotthardt D, Prchal-Murphy M, Seillet C, Glasner A, Mandelboim O, Carotta S, Sexl V, Putz EM. Gotthardt D, et al. Among authors: sexl v. Genes Immun. 2014 Dec;15(8):584-7. doi: 10.1038/gene.2014.55. Epub 2014 Oct 16. Genes Immun. 2014. PMID: 25319498
CDK6 as a key regulator of hematopoietic and leukemic stem cell activation.
Scheicher R, Hoelbl-Kovacic A, Bellutti F, Tigan AS, Prchal-Murphy M, Heller G, Schneckenleithner C, Salazar-Roa M, Zöchbauer-Müller S, Zuber J, Malumbres M, Kollmann K, Sexl V. Scheicher R, et al. Among authors: sexl v. Blood. 2015 Jan 1;125(1):90-101. doi: 10.1182/blood-2014-06-584417. Epub 2014 Oct 23. Blood. 2015. PMID: 25342715 Free PMC article.
In vivo tumor surveillance by NK cells requires TYK2 but not TYK2 kinase activity.
Prchal-Murphy M, Witalisz-Siepracka A, Bednarik KT, Putz EM, Gotthardt D, Meissl K, Sexl V, Müller M, Strobl B. Prchal-Murphy M, et al. Among authors: sexl v. Oncoimmunology. 2015 May 26;4(11):e1047579. doi: 10.1080/2162402X.2015.1047579. eCollection 2015 Nov. Oncoimmunology. 2015. PMID: 26451322 Free PMC article.
STAT5 Is a Key Regulator in NK Cells and Acts as a Molecular Switch from Tumor Surveillance to Tumor Promotion.
Gotthardt D, Putz EM, Grundschober E, Prchal-Murphy M, Straka E, Kudweis P, Heller G, Bago-Horvath Z, Witalisz-Siepracka A, Cumaraswamy AA, Gunning PT, Strobl B, Müller M, Moriggl R, Stockmann C, Sexl V. Gotthardt D, et al. Among authors: sexl v. Cancer Discov. 2016 Apr;6(4):414-29. doi: 10.1158/2159-8290.CD-15-0732. Epub 2016 Feb 12. Cancer Discov. 2016. PMID: 26873347
Repurposing Treprostinil for Enhancing Hematopoietic Progenitor Cell Transplantation.
Kazemi Z, Bergmayr C, Prchal-Murphy M, Javaheri T, Themanns M, Pham HT, Strohmaier W, Sexl V, Freissmuth M, Zebedin-Brandl E. Kazemi Z, et al. Among authors: sexl v. Mol Pharmacol. 2016 Jun;89(6):630-44. doi: 10.1124/mol.116.103267. Epub 2016 Mar 17. Mol Pharmacol. 2016. PMID: 26989084 Free PMC article.
210 results