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Resolving the fibrotic niche of human liver cirrhosis at single-cell level.
Ramachandran P, Dobie R, Wilson-Kanamori JR, Dora EF, Henderson BEP, Luu NT, Portman JR, Matchett KP, Brice M, Marwick JA, Taylor RS, Efremova M, Vento-Tormo R, Carragher NO, Kendall TJ, Fallowfield JA, Harrison EM, Mole DJ, Wigmore SJ, Newsome PN, Weston CJ, Iredale JP, Tacke F, Pollard JW, Ponting CP, Marioni JC, Teichmann SA, Henderson NC. Ramachandran P, et al. Among authors: henderson nc, henderson bep. Nature. 2019 Nov;575(7783):512-518. doi: 10.1038/s41586-019-1631-3. Epub 2019 Oct 9. Nature. 2019. PMID: 31597160 Free PMC article.
Modeling liver fibrosis in rodents.
Constandinou C, Henderson N, Iredale JP. Constandinou C, et al. Methods Mol Med. 2005;117:237-50. doi: 10.1385/1-59259-940-0:237. Methods Mol Med. 2005. PMID: 16118456
Galectin-3 regulates myofibroblast activation and hepatic fibrosis.
Henderson NC, Mackinnon AC, Farnworth SL, Poirier F, Russo FP, Iredale JP, Haslett C, Simpson KJ, Sethi T. Henderson NC, et al. Proc Natl Acad Sci U S A. 2006 Mar 28;103(13):5060-5. doi: 10.1073/pnas.0511167103. Epub 2006 Mar 20. Proc Natl Acad Sci U S A. 2006. PMID: 16549783 Free PMC article.
Standing down the guard: stellate cells leave quietly.
Henderson NC, Iredale JP. Henderson NC, et al. Gastroenterology. 2012 Oct;143(4):890-2. doi: 10.1053/j.gastro.2012.08.014. Epub 2012 Aug 20. Gastroenterology. 2012. PMID: 22917861 No abstract available.
Origins of fibrosis: pericytes take centre stage.
Greenhalgh SN, Iredale JP, Henderson NC. Greenhalgh SN, et al. Among authors: henderson nc. F1000Prime Rep. 2013 Sep 2;5:37. doi: 10.12703/P5-37. F1000Prime Rep. 2013. PMID: 24049641 Free PMC article. Review.
Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs.
Henderson NC, Arnold TD, Katamura Y, Giacomini MM, Rodriguez JD, McCarty JH, Pellicoro A, Raschperger E, Betsholtz C, Ruminski PG, Griggs DW, Prinsen MJ, Maher JJ, Iredale JP, Lacy-Hulbert A, Adams RH, Sheppard D. Henderson NC, et al. Nat Med. 2013 Dec;19(12):1617-24. doi: 10.1038/nm.3282. Epub 2013 Nov 10. Nat Med. 2013. PMID: 24216753 Free PMC article.
152 results