Roskos LK - Search Results

1

Patient-reported outcomes and inflammatory biomarkers in patients with locally advanced/metastatic urothelial carcinoma treated with durvalumab in phase 1/2 dose-escalation study 1108.

O'Donnell PH, Arkenau HT, Sridhar SS, Ong M, Drakaki A, Spira AI, Zhang J, Gordon MS, Degboe AN, Gupta AK, Mukhopadhyay P, Huang W, Abdullah SE, Angra N, Roskos LK, Guo X, Friedlander T. O'Donnell PH, et al. Among authors: roskos lk. Cancer. 2020 Jan 15;126(2):432-443. doi: 10.1002/cncr.32532. Epub 2019 Oct 3. Cancer. 2020. PMID: 31581306 Free article. Clinical Trial.

2

Population Modeling of Tumor Kinetics and Overall Survival to Identify Prognostic and Predictive Biomarkers of Efficacy for Durvalumab in Patients With Urothelial Carcinoma.

Zheng Y, Narwal R, Jin C, Baverel PG, Jin X, Gupta A, Ben Y, Wang B, Mukhopadhyay P, Higgs BW, Roskos L. Zheng Y, et al. Clin Pharmacol Ther. 2018 Apr;103(4):643-652. doi: 10.1002/cpt.986. Epub 2018 Jan 17. Clin Pharmacol Ther. 2018. PMID: 29243222 Free PMC article.

3

Population Pharmacokinetics of Durvalumab in Cancer Patients and Association With Longitudinal Biomarkers of Disease Status.

Baverel PG, Dubois VFS, Jin CY, Zheng Y, Song X, Jin X, Mukhopadhyay P, Gupta A, Dennis PA, Ben Y, Vicini P, Roskos L, Narwal R. Baverel PG, et al. Clin Pharmacol Ther. 2018 Apr;103(4):631-642. doi: 10.1002/cpt.982. Epub 2018 Feb 2. Clin Pharmacol Ther. 2018. PMID: 29243223 Free PMC article.

4

Association of circulating protein biomarkers with clinical outcomes of durvalumab in head and neck squamous cell carcinoma.

Arends R, Guo X, Baverel PG, González-García I, Xie J, Morsli N, Yovine A, Roskos LK. Arends R, et al. Among authors: roskos lk. Oncoimmunology. 2021 Mar 17;10(1):1898104. doi: 10.1080/2162402X.2021.1898104. Oncoimmunology. 2021. PMID: 33796405 Free PMC article.

5

Pharmacodynamic biomarkers and differential effects of TNF- and GM-CSF-targeting biologics in rheumatoid arthritis.

Guo X, Wang S, Godwood A, Close D, Ryan PC, Roskos LK, White WI. Guo X, et al. Among authors: roskos lk. Int J Rheum Dis. 2019 Apr;22(4):646-653. doi: 10.1111/1756-185X.13395. Epub 2018 Oct 24. Int J Rheum Dis. 2019. PMID: 30358109 Free PMC article. Clinical Trial.

6

Suppression of T Cell Activation and Collagen Accumulation by an Anti-IFNAR1 mAb, Anifrolumab, in Adult Patients with Systemic Sclerosis.

Guo X, Higgs BW, Bay-Jensen AC, Karsdal MA, Yao Y, Roskos LK, White WI. Guo X, et al. Among authors: roskos lk. J Invest Dermatol. 2015 Oct;135(10):2402-2409. doi: 10.1038/jid.2015.188. Epub 2015 May 20. J Invest Dermatol. 2015. PMID: 25993119 Free article. Clinical Trial.

7

Suppression of soluble T cell-associated proteins by an anti-interferon-α monoclonal antibody in adult patients with dermatomyositis or polymyositis.

Guo X, Higgs BW, Rebelatto M, Zhu W, Greth W, Yao Y, Roskos LK, White WI. Guo X, et al. Among authors: roskos lk. Rheumatology (Oxford). 2014 Apr;53(4):686-95. doi: 10.1093/rheumatology/ket413. Epub 2013 Dec 19. Rheumatology (Oxford). 2014. PMID: 24357810 Free PMC article. Clinical Trial.

8

Choice of Starting Dose for Biopharmaceuticals in First-in-Human Phase I Cancer Clinical Trials.

Hansen AR, Cook N, Ricci MS, Razak A, Le Tourneau C, McKeever K, Roskos L, Dixit R, Siu LL, Hinrichs MJ. Hansen AR, et al. Oncologist. 2015 Jun;20(6):653-9. doi: 10.1634/theoncologist.2015-0008. Epub 2015 May 11. Oncologist. 2015. PMID: 25964306 Free PMC article.

9

An open-label, single-dose bioavailability study of the pharmacokinetics of CAT-354 after subcutaneous and intravenous administration in healthy males.

Oh CK, Faggioni R, Jin F, Roskos LK, Wang B, Birrell C, Wilson R, Molfino NA. Oh CK, et al. Among authors: roskos lk. Br J Clin Pharmacol. 2010 Jun;69(6):645-55. doi: 10.1111/j.1365-2125.2010.03647.x. Br J Clin Pharmacol. 2010. PMID: 20565456 Free PMC article. Clinical Trial.

10

Relationship Between Benralizumab Exposure and Efficacy for Patients With Severe Eosinophilic Asthma.

Chia YL, Yan L, Yu B, Wang B, Barker P, Goldman M, Roskos L. Chia YL, et al. Clin Pharmacol Ther. 2019 Aug;106(2):383-390. doi: 10.1002/cpt.1371. Epub 2019 Mar 22. Clin Pharmacol Ther. 2019. PMID: 30661249 Free PMC article. Clinical Trial.

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