Lee M - Search Results

1

Antibiotic treatment ameliorates Ten-eleven translocation 2 (TET2) loss-of-function associated hematological malignancies.

Zeng H, He H, Guo L, Li J, Lee M, Han W, Guzman AG, Zang S, Zhou Y, Zhang X, Goodell MA, King KY, Sun D, Huang Y. Zeng H, et al. Among authors: lee m. Cancer Lett. 2019 Dec 28;467:1-8. doi: 10.1016/j.canlet.2019.09.013. Epub 2019 Sep 26. Cancer Lett. 2019. PMID: 31563562 Free PMC article.

2

Tet2 Inactivation Enhances the Antitumor Activity of Tumor-Infiltrating Lymphocytes.

Lee M, Li J, Li J, Fang S, Zhang J, Vo ATT, Han W, Zeng H, Isgandarova S, Martinez-Moczygemba M, Zhou Y, Sun D, Huang Y. Lee M, et al. Cancer Res. 2021 Apr 15;81(8):1965-1976. doi: 10.1158/0008-5472.CAN-20-3213. Epub 2021 Feb 15. Cancer Res. 2021. PMID: 33589517 Free PMC article.

3

Mutations in 5-methylcytosine oxidase TET2 and RhoA cooperatively disrupt T cell homeostasis.

Zang S, Li J, Yang H, Zeng H, Han W, Zhang J, Lee M, Moczygemba M, Isgandarova S, Yang Y, Zhou Y, Rao A, You MJ, Sun D, Huang Y. Zang S, et al. Among authors: lee m. J Clin Invest. 2017 Aug 1;127(8):2998-3012. doi: 10.1172/JCI92026. Epub 2017 Jul 10. J Clin Invest. 2017. PMID: 28691928 Free PMC article.

4

Engineered Split-TET2 Enzyme for Inducible Epigenetic Remodeling.

Lee M, Li J, Liang Y, Ma G, Zhang J, He L, Liu Y, Li Q, Li M, Sun D, Zhou Y, Huang Y. Lee M, et al. J Am Chem Soc. 2017 Apr 5;139(13):4659-4662. doi: 10.1021/jacs.7b01459. Epub 2017 Mar 23. J Am Chem Soc. 2017. PMID: 28294608 Free PMC article.

5

An Engineered Split-TET2 Enzyme for Chemical-inducible DNA Hydroxymethylation and Epigenetic Remodeling.

Lee M, Zhou Y, Huang Y. Lee M, et al. J Vis Exp. 2017 Dec 18;(130):56858. doi: 10.3791/56858. J Vis Exp. 2017. PMID: 29286410 Free PMC article.

6

p53-dependent autophagic degradation of TET2 modulates cancer therapeutic resistance.

Zhang J, Tan P, Guo L, Gong J, Ma J, Li J, Lee M, Fang S, Jing J, Johnson G, Sun D, Cao WM, Dashwood R, Han L, Zhou Y, Dong WG, Huang Y. Zhang J, et al. Among authors: lee m. Oncogene. 2019 Mar;38(11):1905-1919. doi: 10.1038/s41388-018-0524-5. Epub 2018 Nov 2. Oncogene. 2019. PMID: 30390073 Free PMC article.

7

Tet inactivation disrupts YY1 binding and long-range chromatin interactions during embryonic heart development.

Fang S, Li J, Xiao Y, Lee M, Guo L, Han W, Li T, Hill MC, Hong T, Mo W, Xu R, Zhang P, Wang F, Chang J, Zhou Y, Sun D, Martin JF, Huang Y. Fang S, et al. Among authors: lee m. Nat Commun. 2019 Sep 20;10(1):4297. doi: 10.1038/s41467-019-12325-z. Nat Commun. 2019. PMID: 31541101 Free PMC article.

8

A combination strategy targeting enhancer plasticity exerts synergistic lethality against BETi-resistant leukemia cells.

Guo L, Li J, Zeng H, Guzman AG, Li T, Lee M, Zhou Y, Goodell MA, Stephan C, Davies PJA, Dawson MA, Sun D, Huang Y. Guo L, et al. Among authors: lee m. Nat Commun. 2020 Feb 6;11(1):740. doi: 10.1038/s41467-020-14604-6. Nat Commun. 2020. PMID: 32029739 Free PMC article.

9

Systematic Profiling of DNMT3A Variants Reveals Protein Instability Mediated by the DCAF8 E3 Ubiquitin Ligase Adaptor.

Huang YH, Chen CW, Sundaramurthy V, Słabicki M, Hao D, Watson CJ, Tovy A, Reyes JM, Dakhova O, Crovetti BR, Galonska C, Lee M, Brunetti L, Zhou Y, Tatton-Brown K, Huang Y, Cheng X, Meissner A, Valk PJM, Van Maldergem L, Sanders MA, Blundell JR, Li W, Ebert BL, Goodell MA. Huang YH, et al. Among authors: lee m. Cancer Discov. 2022 Jan;12(1):220-235. doi: 10.1158/2159-8290.CD-21-0560. Epub 2021 Aug 24. Cancer Discov. 2022. PMID: 34429321 Free PMC article.

10

Ten-Eleven Translocation Ablation Impairs Cardiac Differentiation of Mouse Embryonic Stem Cells.

Fang S, Cui D, Hong T, Guo L, Lee YT, Lee M, Isgandarova S, Martinez-Moczygemba M, Zhou Y, Li J, Huang Y. Fang S, et al. Among authors: lee yt, lee m. Stem Cells. 2022 Mar 31;40(3):260-272. doi: 10.1093/stmcls/sxab017. Stem Cells. 2022. PMID: 35296897

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