Neutrophil exosomes enhance the skin autoinflammation in generalized pustular psoriasis via activating keratinocytes.
Shao S, Fang H, Zhang J, Jiang M, Xue K, Ma J, Zhang J, Lei J, Zhang Y, Li B, Yuan X, Dang E, Wang G.
Shao S, et al.
FASEB J. 2019 Jun;33(6):6813-6828. doi: 10.1096/fj.201802090RR. Epub 2019 Feb 27.
FASEB J. 2019.
PMID: 30811955
These results demonstrate that neutrophil exosomes have an immune-regulatory effect on keratinocytes, which modulates immune cell migration and autoinflammation in GPP.-Shao, S., Fang, H., Zhang, J., Jiang, M., Xue, K., Ma, J., Zhang, J., Lei, J., Zhang, Y., Li, B., …
These results demonstrate that neutrophil exosomes have an immune-regulatory effect on keratinocytes, which modulates immune cell migration …