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A multi-modal single-cell and spatial expression map of metastatic breast cancer biopsies across clinicopathological features.
Klughammer J, Abravanel DL, Segerstolpe Å, Blosser TR, Goltsev Y, Cui Y, Goodwin DR, Sinha A, Ashenberg O, Slyper M, Vigneau S, Jané-Valbuena J, Alon S, Caraccio C, Chen J, Cohen O, Cullen N, DelloStritto LK, Dionne D, Files J, Frangieh A, Helvie K, Hughes ME, Inga S, Kanodia A, Lako A, MacKichan C, Mages S, Moriel N, Murray E, Napolitano S, Nguyen K, Nitzan M, Ortiz R, Patel M, Pfaff KL, Porter CBM, Rotem A, Strauss S, Strasser R, Thorner AR, Turner M, Wakiro I, Waldman J, Wu J, Gómez Tejeda Zañudo J, Zhang D, Lin NU, Tolaney SM, Winer EP, Boyden ES, Chen F, Nolan GP, Rodig SJ, Zhuang X, Rozenblatt-Rosen O, Johnson BE, Regev A, Wagle N. Klughammer J, et al. Among authors: napolitano s. Nat Med. 2024 Nov;30(11):3236-3249. doi: 10.1038/s41591-024-03215-z. Epub 2024 Oct 30. Nat Med. 2024. PMID: 39478111 Free PMC article.
Epigenome Reprogramming Through H3K27 and H3K4 Trimethylation as a Resistance Mechanism to DNA Methylation Inhibition in BRAFV600E-Mutated Colorectal Cancer.
Lee HM, Saw AK, Morris VK, Napolitano S, Bristow C, Srinivasan S, Peoples M, Sorokin A, Kanikarla Marie P, Schulz J, Singh AK, Terranova C, Coker O, Jain A, Kopetz S, Rai K. Lee HM, et al. Among authors: napolitano s. Clin Cancer Res. 2024 Nov 15;30(22):5166-5179. doi: 10.1158/1078-0432.CCR-24-1166. Clin Cancer Res. 2024. PMID: 39269307
Comprehensive genomic profiling by liquid biopsy captures tumor heterogeneity and identifies cancer vulnerabilities in patients with RAS/BRAFV600E wild-type metastatic colorectal cancer in the CAPRI 2-GOIM trial.
Ciardiello D, Boscolo Bielo L, Napolitano S, Martinelli E, Troiani T, Nicastro A, Latiano TP, Parente P, Maiello E, Avallone A, Normanno N, Pisconti S, Nisi C, Bordonaro R, Russo AE, Tamburini E, Toma I, Lotesoriere C, Vallarelli S, Zampino MG, Fazio N, Curigliano G, De Vita F, Ciardiello F, Martini G; CAPRI-2 GOIM study group. Ciardiello D, et al. Among authors: napolitano s. Ann Oncol. 2024 Aug 29:S0923-7534(24)03914-0. doi: 10.1016/j.annonc.2024.08.2334. Online ahead of print. Ann Oncol. 2024. PMID: 39214459
Overexpression of CCL-20 and CXCL-8 genes enhances tumor escape and resistance to cemiplimab, a programmed cell death protein-1 (PD-1) inhibitor, in patients with locally advanced and metastatic cutaneous squamous cell carcinoma.
De Falco V, Napolitano S, Franco R, Zito Marino F, Formisano L, Esposito D, Suarato G, Napolitano R, Esposito A, Caraglia F, Giugliano MC, Cioli E, Famiglietti V, Bianco R, Argenziano G, Ronchi A, Ciardiello D, Nardone V, D'Ippolito E, Del Tufo S, Ciardiello F, Troiani T. De Falco V, et al. Among authors: napolitano s. Oncoimmunology. 2024 Aug 26;13(1):2388315. doi: 10.1080/2162402X.2024.2388315. eCollection 2024. Oncoimmunology. 2024. PMID: 39206096 Free PMC article.
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