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The transcribed pseudogene RPSAP52 enhances the oncofetal HMGA2-IGF2BP2-RAS axis through LIN28B-dependent and independent let-7 inhibition.
Oliveira-Mateos C, Sánchez-Castillo A, Soler M, Obiols-Guardia A, Piñeyro D, Boque-Sastre R, Calleja-Cervantes ME, Castro de Moura M, Martínez-Cardús A, Rubio T, Pelletier J, Martínez-Iniesta M, Herrero-Martín D, Tirado OM, Gentilella A, Villanueva A, Esteller M, Farré L, Guil S. Oliveira-Mateos C, et al. Among authors: esteller m. Nat Commun. 2019 Sep 4;10(1):3979. doi: 10.1038/s41467-019-11910-6. Nat Commun. 2019. PMID: 31484926 Free PMC article.
A microRNA DNA methylation signature for human cancer metastasis.
Lujambio A, Calin GA, Villanueva A, Ropero S, Sánchez-Céspedes M, Blanco D, Montuenga LM, Rossi S, Nicoloso MS, Faller WJ, Gallagher WM, Eccles SA, Croce CM, Esteller M. Lujambio A, et al. Among authors: esteller m. Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13556-61. doi: 10.1073/pnas.0803055105. Epub 2008 Sep 3. Proc Natl Acad Sci U S A. 2008. PMID: 18768788 Free PMC article.
A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function.
Melo SA, Ropero S, Moutinho C, Aaltonen LA, Yamamoto H, Calin GA, Rossi S, Fernandez AF, Carneiro F, Oliveira C, Ferreira B, Liu CG, Villanueva A, Capella G, Schwartz S Jr, Shiekhattar R, Esteller M. Melo SA, et al. Among authors: esteller m. Nat Genet. 2009 Mar;41(3):365-70. doi: 10.1038/ng.317. Epub 2009 Feb 15. Nat Genet. 2009. Retraction in: Nat Genet. 2016 Feb;48(2):221. doi: 10.1038/ng0216-221. PMID: 19219043 Free PMC article. Retracted.
Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing.
Melo S, Villanueva A, Moutinho C, Davalos V, Spizzo R, Ivan C, Rossi S, Setien F, Casanovas O, Simo-Riudalbas L, Carmona J, Carrere J, Vidal A, Aytes A, Puertas S, Ropero S, Kalluri R, Croce CM, Calin GA, Esteller M. Melo S, et al. Among authors: esteller m. Proc Natl Acad Sci U S A. 2011 Mar 15;108(11):4394-9. doi: 10.1073/pnas.1014720108. Epub 2011 Feb 28. Proc Natl Acad Sci U S A. 2011. PMID: 21368194 Free PMC article.
A DNA methylation fingerprint of 1628 human samples.
Fernandez AF, Assenov Y, Martin-Subero JI, Balint B, Siebert R, Taniguchi H, Yamamoto H, Hidalgo M, Tan AC, Galm O, Ferrer I, Sanchez-Cespedes M, Villanueva A, Carmona J, Sanchez-Mut JV, Berdasco M, Moreno V, Capella G, Monk D, Ballestar E, Ropero S, Martinez R, Sanchez-Carbayo M, Prosper F, Agirre X, Fraga MF, Graña O, Perez-Jurado L, Mora J, Puig S, Prat J, Badimon L, Puca AA, Meltzer SJ, Lengauer T, Bridgewater J, Bock C, Esteller M. Fernandez AF, et al. Among authors: esteller m. Genome Res. 2012 Feb;22(2):407-19. doi: 10.1101/gr.119867.110. Epub 2011 May 25. Genome Res. 2012. PMID: 21613409 Free PMC article.
Antitumor activity of a small-molecule inhibitor of the histone kinase Haspin.
Huertas D, Soler M, Moreto J, Villanueva A, Martinez A, Vidal A, Charlton M, Moffat D, Patel S, McDermott J, Owen J, Brotherton D, Krige D, Cuthill S, Esteller M. Huertas D, et al. Among authors: esteller m. Oncogene. 2012 Mar 15;31(11):1408-18. doi: 10.1038/onc.2011.335. Epub 2011 Aug 1. Oncogene. 2012. PMID: 21804608 Free PMC article.
770 results