Yang KY - Search Results

1

Physapubescin I from husk tomato suppresses SW1990 cancer cell growth by targeting kidney-type glutaminase.

Yang KY, Wu CR, Zheng MZ, Tang RT, Li XZ, Chen LX, Li H. Yang KY, et al. Bioorg Chem. 2019 Nov;92:103186. doi: 10.1016/j.bioorg.2019.103186. Epub 2019 Aug 12. Bioorg Chem. 2019. PMID: 31465967

2

Steroids from Ganoderma sinense as new natural inhibitors of cancer-associated mutant IDH1.

Zheng M, Tang R, Deng Y, Yang K, Chen L, Li H. Zheng M, et al. Bioorg Chem. 2018 Sep;79:89-97. doi: 10.1016/j.bioorg.2018.04.016. Epub 2018 Apr 30. Bioorg Chem. 2018. PMID: 29738972

3

Identification of a pyrimidinetrione derivative as the potent DprE1 inhibitor by structure-based virtual ligand screening.

Gao Y, Xie J, Tang R, Yang K, Zhang Y, Chen L, Li H. Gao Y, et al. Bioorg Chem. 2019 Apr;85:168-178. doi: 10.1016/j.bioorg.2018.12.018. Epub 2018 Dec 13. Bioorg Chem. 2019. PMID: 30616098

4

Ixocarpalactone A from dietary tomatillo inhibits pancreatic cancer growth by targeting PHGDH.

Zheng M , Guo J , Xu J , Yang K , Tang R , Gu X , Li H , Chen L . Zheng M , et al. Food Funct. 2019 Jun 19;10(6):3386-3395. doi: 10.1039/c9fo00394k. Food Funct. 2019. PMID: 31112178

5

Adapalene inhibits ovarian cancer ES-2 cells growth by targeting glutamic-oxaloacetic transaminase 1.

Wang Q, Zhang Q, Luan S, Yang K, Zheng M, Li K, Chen L, Li H. Wang Q, et al. Bioorg Chem. 2019 Dec;93:103315. doi: 10.1016/j.bioorg.2019.103315. Epub 2019 Sep 26. Bioorg Chem. 2019. PMID: 31605927

6

Structure based discovery of novel hexokinase 2 inhibitors.

Liu Y, Li M, Zhang Y, Wu C, Yang K, Gao S, Zheng M, Li X, Li H, Chen L. Liu Y, et al. Bioorg Chem. 2020 Mar;96:103609. doi: 10.1016/j.bioorg.2020.103609. Epub 2020 Jan 21. Bioorg Chem. 2020. PMID: 32007722

7

Novel selective hexokinase 2 inhibitor Benitrobenrazide blocks cancer cells growth by targeting glycolysis.

Zheng M, Wu C, Yang K, Yang Y, Liu Y, Gao S, Wang Q, Li C, Chen L, Li H. Zheng M, et al. Pharmacol Res. 2021 Feb;164:105367. doi: 10.1016/j.phrs.2020.105367. Epub 2020 Dec 8. Pharmacol Res. 2021. PMID: 33307221

8

Novel PROTACs for degradation of SHP2 protein.

Zheng M, Liu Y, Wu C, Yang K, Wang Q, Zhou Y, Chen L, Li H. Zheng M, et al. Bioorg Chem. 2021 May;110:104788. doi: 10.1016/j.bioorg.2021.104788. Epub 2021 Mar 1. Bioorg Chem. 2021. PMID: 33706076

9

Discovery of linear unnatural peptides as potent mutant isocitrate dehydrogenase 1 inhibitors by Ugi reaction.

Zhou X, Zheng M, Zhao N, Hu Y, Yang K, Huo J, Liu G, Huang J, Chen L, Zhou Y, Li H. Zhou X, et al. Bioorg Chem. 2022 Feb;119:105569. doi: 10.1016/j.bioorg.2021.105569. Epub 2021 Dec 20. Bioorg Chem. 2022. PMID: 34954572

10

New natural inhibitors of hexokinase 2 (HK2): Steroids from Ganoderma sinense.

Bao F, Yang K, Wu C, Gao S, Wang P, Chen L, Li H. Bao F, et al. Fitoterapia. 2018 Mar;125:123-129. doi: 10.1016/j.fitote.2018.01.001. Epub 2018 Jan 4. Fitoterapia. 2018. PMID: 29305912

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