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Machine learning uncovers cell identity regulator by histone code.
Xia B, Zhao D, Wang G, Zhang M, Lv J, Tomoiaga AS, Li Y, Wang X, Meng S, Cooke JP, Cao Q, Zhang L, Chen K. Xia B, et al. Among authors: wang x, wang g. Nat Commun. 2020 Jun 1;11(1):2696. doi: 10.1038/s41467-020-16539-4. Nat Commun. 2020. PMID: 32483223 Free PMC article.
Antihistamine Drug Ebastine Inhibits Cancer Growth by Targeting Polycomb Group Protein EZH2.
Li Q, Liu KY, Liu Q, Wang G, Jiang W, Meng Q, Yi Y, Yang Y, Wang R, Zhu S, Li C, Wu L, Zhao D, Yan L, Zhang L, Kim JS, Zu X, Kozielski AJ, Qian W, Chang JC, Patnaik A, Chen K, Cao Q. Li Q, et al. Among authors: wang g, wang r. Mol Cancer Ther. 2020 Oct;19(10):2023-2033. doi: 10.1158/1535-7163.MCT-20-0250. Epub 2020 Aug 27. Mol Cancer Ther. 2020. PMID: 32855270 Free PMC article.
Broad genic repression domains signify enhanced silencing of oncogenes.
Zhao D, Zhang L, Zhang M, Xia B, Lv J, Gao X, Wang G, Meng Q, Yi Y, Zhu S, Tomoiaga AS, Lee MG, Cooke JP, Cao Q, Chen K. Zhao D, et al. Among authors: wang g. Nat Commun. 2020 Nov 3;11(1):5560. doi: 10.1038/s41467-020-18913-8. Nat Commun. 2020. PMID: 33144558 Free PMC article.
MACMIC Reveals A Dual Role of CTCF in Epigenetic Regulation of Cell Identity Genes.
Wang G, Xia B, Zhou M, Lv J, Zhao D, Li Y, Bu Y, Wang X, Cooke JP, Cao Q, Lee MG, Zhang L, Chen K. Wang G, et al. Among authors: wang x. Genomics Proteomics Bioinformatics. 2021 Feb;19(1):140-153. doi: 10.1016/j.gpb.2020.10.008. Epub 2021 Mar 5. Genomics Proteomics Bioinformatics. 2021. PMID: 33677108 Free PMC article.
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