Liang SQ - Search Results

1

Tissue-restricted genome editing in vivo specified by microRNA-repressible anti-CRISPR proteins.

Lee J, Mou H, Ibraheim R, Liang SQ, Liu P, Xue W, Sontheimer EJ. Lee J, et al. Among authors: liang sq. RNA. 2019 Nov;25(11):1421-1431. doi: 10.1261/rna.071704.119. Epub 2019 Aug 22. RNA. 2019. PMID: 31439808 Free PMC article.

2

YAP1 Withdrawal in Hepatoblastoma Drives Therapeutic Differentiation of Tumor Cells to Functional Hepatocyte-Like Cells.

Smith JL, Rodríguez TC, Mou H, Kwan SY, Pratt H, Zhang XO, Cao Y, Liang S, Ozata DM, Yu T, Yin Q, Hazeltine M, Weng Z, Sontheimer EJ, Xue W. Smith JL, et al. Hepatology. 2021 Mar;73(3):1011-1027. doi: 10.1002/hep.31389. Epub 2021 Feb 8. Hepatology. 2021. PMID: 32452550 Free PMC article.

3

Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice.

Liu P, Liang SQ, Zheng C, Mintzer E, Zhao YG, Ponnienselvan K, Mir A, Sontheimer EJ, Gao G, Flotte TR, Wolfe SA, Xue W. Liu P, et al. Among authors: liang sq. Nat Commun. 2021 Apr 9;12(1):2121. doi: 10.1038/s41467-021-22295-w. Nat Commun. 2021. PMID: 33837189 Free PMC article.

4

AAV5 delivery of CRISPR-Cas9 supports effective genome editing in mouse lung airway.

Liang SQ, Walkey CJ, Martinez AE, Su Q, Dickinson ME, Wang D, Lagor WR, Heaney JD, Gao G, Xue W. Liang SQ, et al. Mol Ther. 2022 Jan 5;30(1):238-243. doi: 10.1016/j.ymthe.2021.10.023. Epub 2021 Oct 23. Mol Ther. 2022. PMID: 34695545 Free PMC article.

5

A flexible split prime editor using truncated reverse transcriptase improves dual-AAV delivery in mouse liver.

Zheng C, Liang SQ, Liu B, Liu P, Kwan SY, Wolfe SA, Xue W. Zheng C, et al. Among authors: liang sq. Mol Ther. 2022 Mar 2;30(3):1343-1351. doi: 10.1016/j.ymthe.2022.01.005. Epub 2022 Jan 5. Mol Ther. 2022. PMID: 34998953 Free PMC article.

6

Genome-wide detection of CRISPR editing in vivo using GUIDE-tag.

Liang SQ, Liu P, Smith JL, Mintzer E, Maitland S, Dong X, Yang Q, Lee J, Haynes CM, Zhu LJ, Watts JK, Sontheimer EJ, Wolfe SA, Xue W. Liang SQ, et al. Nat Commun. 2022 Jan 21;13(1):437. doi: 10.1038/s41467-022-28135-9. Nat Commun. 2022. PMID: 35064134 Free PMC article.

7

A split prime editor with untethered reverse transcriptase and circular RNA template.

Liu B, Dong X, Cheng H, Zheng C, Chen Z, Rodríguez TC, Liang SQ, Xue W, Sontheimer EJ. Liu B, et al. Among authors: liang sq. Nat Biotechnol. 2022 Sep;40(9):1388-1393. doi: 10.1038/s41587-022-01255-9. Epub 2022 Apr 4. Nat Biotechnol. 2022. PMID: 35379962

8

Combinatorial design of nanoparticles for pulmonary mRNA delivery and genome editing.

Li B, Manan RS, Liang SQ, Gordon A, Jiang A, Varley A, Gao G, Langer R, Xue W, Anderson D. Li B, et al. Among authors: liang sq. Nat Biotechnol. 2023 Oct;41(10):1410-1415. doi: 10.1038/s41587-023-01679-x. Epub 2023 Mar 30. Nat Biotechnol. 2023. PMID: 36997680 Free PMC article.

9

Genome-wide profiling of prime editor off-target sites in vitro and in vivo using PE-tag.

Liang SQ, Liu P, Ponnienselvan K, Suresh S, Chen Z, Kramme C, Chatterjee P, Zhu LJ, Sontheimer EJ, Xue W, Wolfe SA. Liang SQ, et al. Nat Methods. 2023 Jun;20(6):898-907. doi: 10.1038/s41592-023-01859-2. Epub 2023 May 8. Nat Methods. 2023. PMID: 37156841

10

All types of base conversions allowed by base editors.

Liang SQ, Xue W. Liang SQ, et al. Sci China Life Sci. 2024 Feb;67(2):431-433. doi: 10.1007/s11427-023-2435-9. Epub 2023 Nov 2. Sci China Life Sci. 2024. PMID: 37930476 No abstract available.

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